eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa, ELISA Kit

Human Translation initiation factor eIF-2B subunit beta (EIF2B2) ELISA kit; EIF-2Bbeta; EIF2B; ; eukaryotic translation initiation factor 2B; subunit 2 beta; 39kDa

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of EIF2B2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9332948 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa (EIF2B2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EIF2B2. The ELISA analytical biochemical technique of the MBS9332948 kit is based on EIF2B2 antibody-EIF2B2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EIF2B2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EIF2B2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

38,990 Da

eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa

translation initiation factor eIF-2B subunit beta; S20I15; S20III15; eIF-2B GDP-GTP exchange factor subunit beta

Translation initiation factor eIF-2B subunit beta

EIF2BB  [Similar Products]

EI2BB_HUMAN

This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. [provided by RefSeq, Aug 2011]

eIF2B-beta: eukaryotic translation initiation factor 2B, subunit 5. A translational regulatory protein that functions in the early steps of protein synthesis by catalyzing the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutation in EIF2B5 causes childhood ataxia with central nervous system hypomyelination/ vanishing white matter leukodystrophy.

Protein type: GEFs; GEFs, misc.; Translation; Cell development/differentiation; RNA-binding

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: eukaryotic translation initiation factor 2B complex; cytoplasm; cytosol

Molecular Function: protein binding; GTP binding; translation initiation factor activity; guanyl-nucleotide exchange factor activity; S-methyl-5-thioribose-1-phosphate isomerase activity; ATP binding

Biological Process: myelination; response to peptide hormone stimulus; central nervous system development; translation; cellular response to stimulus; cellular protein metabolic process; ovarian follicle development; methionine salvage; response to heat; response to glucose stimulus; translational initiation; gene expression; oligodendrocyte development; regulation of translational initiation; positive regulation of GTPase activity

Disease: Leukoencephalopathy With Vanishing White Matter

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