Octamer Binding Transcription Factor 1 (OCT1), Polyclonal Antibody

POU2F1; OTF1; NF-A1; POU Domain, Class 2, Transcription Factor 1; Octamer-binding transcription factor 1

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

200ug/ml (lot specific)

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Small volumes of anti-10/1/2017 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

33,491 Da

POU class 4 homeobox 1

POU domain, class 4, transcription factor 1

POU domain, class 4, transcription factor 1

Brain-3A; Brn-3A  [Similar Products]

This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some ***** acute myeloid leukemias. [provided by RefSeq, Mar 2012]

POU4F1: Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Belongs to the POU transcription factor family. Class- 4 subfamily.

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q31.1

Cellular Component: nucleoplasm

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; single-stranded DNA binding

Biological Process: axonogenesis; negative regulation of neuron apoptosis; negative regulation of transcription from RNA polymerase II promoter; neurite development; neuron fate specification; peripheral nervous system neuron development; positive regulation of transcription from RNA polymerase II promoter; sensory system development; synaptogenesis; trigeminal nerve development

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