Product Name
Cytokeratin 14 (KRT14), Monoclonal Antibody
Full Product Name
Anti-Cytokeratin 14 Antibody
Product Gene Name
anti-KRT14 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P02533
Specificity
Human Cytokeratin 14 polypeptide
Purity/Purification
Affinity-purified from hybridoma supernatant by affinity-chromatography.
Concentration
100ug/100ul (lot specific)
Immunogen
Human cellus keratin
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.
For extended storage, aliquot contents and freeze at -20 degree C or below.
Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Other Notes
Small volumes of anti-KRT14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-KRT14 antibody
Cytokeratin 14, encoded by the KRT14 gene, is usually found as a heterotetramer with two keratin 5 molecules which form the cytoskeleton of epithelial cells. Mutations in this gene are associated with diseases including epidermolysis bullosa simplex and Naegeli-Franceschetti-Jadassohn syndrome. The Anti-Cytokeratin 14 Antibody is useful in distinguishing stratified epithelial cells from simple epithelial cells. This antibody is also able to recognize basal cell carcinomas and squamous cell carcinomas.
Applications Tested/Suitable for anti-KRT14 antibody
Immunohistochemistry (IHC), Immunoblot (IB)
Application Notes for anti-KRT14 antibody
IHC: 1:50-1:100
IB: 1:100-1:200
NCBI/Uniprot data below describe general gene information for KRT14. It may not necessarily be applicable to this product.
NCBI Accession #
EHH24961.1
[Other Products]
UniProt Primary Accession #
P02533
[Other Products]
UniProt Secondary Accession #
Q14715; Q53XY3; Q9BUE3; Q9UBN2; Q9UBN3; Q9UCY4[Other Products]
Molecular Weight
51,561 Da[Similar Products]
NCBI Official Full Name
Cytokeratin-14
UniProt Protein Name
Keratin, type I cytoskeletal 14
UniProt Synonym Protein Names
Cytokeratin-14; CK-14; Keratin-14; K14
UniProt Gene Name
KRT14 [Similar Products]
UniProt Synonym Gene Names
CK-14; K14 [Similar Products]
UniProt Comments for KRT14
The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
