Full Product Name
AHI1 Antibody, HRP Conjugated
Product Synonym Names
Jouberin; Abelson helper integration site 1 protein homolog; AHI-1; AHI1
Product Gene Name
anti-AHI1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8N157
Purity/Purification
>95%
Protein G Purified
Immunogen
Recombinant Human Jouberin protein (1-213AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at-20 degree C or-80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-AHI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-AHI1 antibody
Cell Biology
Applications Tested/Suitable for anti-AHI1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for AHI1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001128302.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001134830.1
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UniProt Primary Accession #
Q8N157
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UniProt Secondary Accession #
Q4FD35; Q504T3; Q5TCP9; Q6P098; Q6PIT6; Q8NDX0; Q9H0H2; E1P584[Other Products]
UniProt Related Accession #
Q8N157[Other Products]
Molecular Weight
120,853 Da
NCBI Official Full Name
jouberin isoform a
NCBI Official Synonym Full Names
Abelson helper integration site 1
NCBI Official Symbol
AHI1 [Similar Products]
NCBI Official Synonym Symbols
ORF1; AHI-1; JBTS3; dJ71N10.1
[Similar Products]
NCBI Protein Information
jouberin
UniProt Protein Name
Jouberin
UniProt Synonym Protein Names
Abelson helper integration site 1 protein homolog; AHI-1
UniProt Gene Name
AHI1 [Similar Products]
UniProt Synonym Gene Names
AHI-1 [Similar Products]
NCBI Summary for AHI1
This gene is apparently required for both cerebellar and cortical development in humans. This gene mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
UniProt Comments for AHI1
Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development (PubMed:21623382).
Research Articles on AHI1
1. Two copies of the MS risk allele within AHI1 (rs11154801) is associated with increased relapses among children and *****s.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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