Product Name
MCCC2, Blocking Peptide
Full Product Name
MCCC2 Peptide - N-terminal region
Product Gene Name
MCCC2 blocking peptide
[Similar Products]
MCCC2 peptide (MBS3233118) is used for blocking the activity of MCCC2 antibody (MBS3208155)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: LPRERIDNLI DPGSPFLELS QFAGYQLYDN EEVPGGGIIT GIGRVSGVEC
3D Structure
ModBase 3D Structure for Q9HCC0
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of MCCC2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MCCC2 blocking peptide
This is a synthetic peptide designed for use in combination with anti-MCCC2 Antibody, made
Target Description: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.
Product Categories/Family for MCCC2 blocking peptide
Peptide
Applications Tested/Suitable for MCCC2 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for MCCC2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_071415.1
[Other Products]
NCBI GenBank Nucleotide #
NM_022132.5
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UniProt Primary Accession #
Q9HCC0
[Other Products]
UniProt Related Accession #
Q9HCC0[Other Products]
NCBI Official Full Name
methylcrotonoyl-CoA carboxylase beta chain, mitochondrial isoform 1
NCBI Official Synonym Full Names
methylcrotonoyl-CoA carboxylase 2
NCBI Official Symbol
MCCC2 [Similar Products]
NCBI Official Synonym Symbols
MCCB
[Similar Products]
NCBI Protein Information
methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
UniProt Protein Name
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
UniProt Synonym Protein Names
3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta
Protein Family
Methylcrotonoyl-CoA carboxylase
UniProt Gene Name
MCCC2 [Similar Products]
UniProt Synonym Gene Names
MCCB; MCCase subunit beta [Similar Products]
UniProt Entry Name
MCCB_HUMAN
NCBI Summary for MCCC2
This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]
Research Articles on MCCC2
1. This study reports data mainly obtained from the Portuguese newborn screening program collected over a ten-year period. Analysis of the MCCC1 and MCCC2 genes yielded 26 previously unreported mutations and a variant of clinically unknown significance.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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