Product Name
EFNB1 (Phospho-Tyr317), Antibody
Full Product Name
Rabbit EFNB1 (Phospho-Tyr317) Antibody
Product Gene Name
anti-EFNB1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: X; NC_000023.10 (68048840..68062007). Location: Xq12
3D Structure
ModBase 3D Structure for P98172
Species Reactivity
Human, mouse, rat
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Other Notes
Small volumes of anti-EFNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-EFNB1 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for EFNB1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004420.1
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NCBI GenBank Nucleotide #
NM_004429.4
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UniProt Primary Accession #
P98172
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UniProt Secondary Accession #
D3DVU0[Other Products]
UniProt Related Accession #
P98172[Other Products]
Molecular Weight
38,007 Da
NCBI Official Full Name
ephrin-B1
NCBI Official Synonym Full Names
ephrin-B1
NCBI Official Symbol
EFNB1 [Similar Products]
NCBI Official Synonym Symbols
CFND; CFNS; EFL3; EPLG2; Elk-L; LERK2
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NCBI Protein Information
ephrin-B1; EFL-3; LERK-2; ELK ligand; ligand of eph-related kinase 2; eph-related receptor tyrosine kinase ligand 2
UniProt Protein Name
Ephrin-B1
UniProt Synonym Protein Names
EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2
UniProt Gene Name
EFNB1 [Similar Products]
UniProt Synonym Gene Names
EFL3; EPLG2; LERK2; ELK-L; LERK-2 [Similar Products]
UniProt Entry Name
EFNB1_HUMAN
NCBI Summary for EFNB1
The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008]
UniProt Comments for EFNB1
EFNB1: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphB1 and EphA1. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B1 may play a role in cell adhesion and functions in the development or maintenance of the nervous system. Binding to its receptor induces the collapse of commissural axons/growth cones in vitro. Induced by TNF-alpha. Expressed in brain, heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
Protein type: Membrane protein, integral; Ligand, receptor tyrosine kinase
Chromosomal Location of Human Ortholog: Xq12
Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; synapse; nucleus; lipid raft
Molecular Function: protein binding; ephrin receptor binding
Biological Process: axon guidance; cell-cell signaling; ephrin receptor signaling pathway; positive regulation of T cell proliferation; cell adhesion; embryonic pattern specification; neural crest cell migration
Disease: Craniofrontonasal Syndrome
Research Articles on EFNB1
1. These results indicate a novel function of Nm23-H1 to control contact inhibition of locomotion, and its negative regulation by ephrin-B1.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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