Full Product Name
Cd207 Antibody, Biotin conjugated
Product Synonym Names
C-type lectin domain family 4 member K; Langerin; CD207; Cd207; Clec4k
Product Gene Name
anti-Cd207 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8VBX4
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Mouse C-type lectin domain family 4 member K protein (63-331AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-Cd207 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Cd207 antibody
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.
Applications Tested/Suitable for anti-Cd207 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for Cd207. It may not necessarily be applicable to this product.
NCBI Accession #
NP_659192.2
[Other Products]
NCBI GenBank Nucleotide #
NM_144943.3
[Other Products]
UniProt Primary Accession #
Q8VBX4
[Other Products]
UniProt Secondary Accession #
Q8R442[Other Products]
UniProt Related Accession #
Q8VBX4[Other Products]
Molecular Weight
37,621 Da
NCBI Official Full Name
C-type lectin domain family 4 member K
NCBI Official Synonym Full Names
CD207 antigen
NCBI Official Symbol
Cd207 [Similar Products]
NCBI Protein Information
C-type lectin domain family 4 member K
UniProt Protein Name
C-type lectin domain family 4 member K
UniProt Synonym Protein Names
Langerin; CD_antigen: CD207
Protein Family
C-type lectin domain family
UniProt Gene Name
Cd207 [Similar Products]
UniProt Synonym Gene Names
Clec4k [Similar Products]
UniProt Comments for Cd207
langerin: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. Homotrimer. Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 6|6 C3
Cellular Component: integral to plasma membrane
Molecular Function: carbohydrate binding
Biological Process: defense response to virus
Research Articles on Cd207
1. Data show that Candida albicans and Candida tropicalis preferentially localized in (and persisted within) a sub- population of Peyer's patch Langerin-positive dendritic cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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