Full Product Name
CHIA1 Antibody - middle region
Product Gene Name
anti-CHIA1 antibody
[Similar Products]
Product Synonym Gene Name
YNL; Chia; AMCase; 2200003E03Rik[Similar Products]
Antibody/Peptide Pairs
CHIA1 peptide (MBS3248160) is used for blocking the activity of CHIA1 antibody (MBS3223545)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: APFTTMVSTS QNRQTFITSV IKFLRQYGFD GLDLDWEYPG SRGSPPQDKH
3D Structure
ModBase 3D Structure for Q91XA9
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of mouse CHIA
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-CHIA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-CHIA1 antibody
Polyclonal; Lymphocyte Signaling; Immunology; Apoptosis;
Applications Tested/Suitable for anti-CHIA1 antibody
Western Blot (WB)
Western Blot (WB) of anti-CHIA1 antibody
Host: Rabbit
Target Name: CHIA
Sample Tissue: Mouse Lung lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for CHIA1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_075675.2
[Other Products]
NCBI GenBank Nucleotide #
NM_023186.3
[Other Products]
UniProt Primary Accession #
Q91XA9
[Other Products]
UniProt Related Accession #
Q91XA9[Other Products]
NCBI Official Full Name
acidic mammalian chitinase
NCBI Official Synonym Full Names
chitinase, acidic 1
NCBI Official Symbol
Chia1 [Similar Products]
NCBI Official Synonym Symbols
YNL; Chia; AMCase; 2200003E03Rik
[Similar Products]
NCBI Protein Information
acidic mammalian chitinase
UniProt Protein Name
Acidic mammalian chitinase
UniProt Synonym Protein Names
YNL
UniProt Gene Name
Chia [Similar Products]
UniProt Synonym Gene Names
Chia1; AMCase [Similar Products]
UniProt Entry Name
CHIA_MOUSE
UniProt Comments for CHIA1
CHIA: Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding. Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Secreted; Hydrolase; Secreted, signal peptide; EC 3.2.1.14
Cellular Component: extracellular space; cytoplasm; extracellular region
Molecular Function: hydrolase activity; hydrolase activity, acting on glycosyl bonds; chitin binding; chitinase activity; kinase binding; hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process: polysaccharide catabolic process; apoptosis; metabolic process; production of molecular mediator of acute inflammatory response; immune system process; carbohydrate metabolic process; immune response; chitin catabolic process; inflammatory response; chitin metabolic process
Research Articles on CHIA1
1. The results indicate that mouse AMCase catalyzes hydrolysis as well as transglycosylation and suggest that this enzyme can play a novel role under physiological conditions in peripheral tissues, such as the lungs.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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