Fraser syndrome 1, ELISA Kit

Human Extracellular matrix protein FRAS1 (FRAS1) ELISA kit; DKFZp686I05113; DKFZp686P08111; FLJ14927; FLJ22031; KIAA1500; Fraser syndrome 1 protein; extracellular matrix protein FRAS1; Fraser syndrome 1

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of FRAS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9340582 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fraser syndrome 1 (FRAS1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FRAS1. The ELISA analytical biochemical technique of the MBS9340582 kit is based on FRAS1 antibody-FRAS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FRAS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FRAS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

443,214 Da

Fraser extracellular matrix complex subunit 1

extracellular matrix protein FRAS1; Fraser syndrome 1

Extracellular matrix protein FRAS1

KIAA1500  [Similar Products]

FRAS1_HUMAN

This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development. Mutations in this gene cause Fraser syndrome, a multisystem malformation that can include craniofacial, urogenital and respiratory system abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

FRAS1: Defects in FRAS1 are a cause of Fraser syndrome (FRASS). Fraser syndrome is a multisystem malformation usually comprising cryptophthalmos, cutaneous syndactyly, ear abnormalities, renal agenesis and congenital heart defects. Belongs to the FRAS1 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Extracellular matrix; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q21.21

Cellular Component: extracellular matrix; plasma membrane; integral to membrane

Molecular Function: metal ion binding

Biological Process: skin development; protein transport; morphogenesis of an epithelium; cell communication; palate development; embryonic limb morphogenesis

Disease: Fraser Syndrome

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