Product Name
CD36, cDNA Clone
Full Product Name
CD36 cDNA Clone
Product Gene Name
CD36 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgggctgtg accggaactg tgggctcatc gctggggctg tcattggtgc tgtcctggct gtgtttggag gtattctaat gccagttgga gacctgctta tccagaagac aattaaaaag caagttgtcc tcgaagaagg tacaattgct tttaaaaatt gggttaaaac aggcacagaa gtttacagac agttttggat ctttgatgtg caaaatccac aggaagtgat gatgaacagc agcaacattc aagttaagca aagaggtcct tatacgtaca gagttcgttt tctagccaag gaaaatgtaa cccaggacgc tgaggacaac acagtctctt tcctgcagcc caatggtgcc atcttcgaac cttcactatc agttggaaca gaggctgaca acttcacagt tctcaatctg gctgtggcag ctgcatccca tatctatcaa aatcaatttg ttcaaatgat cctcaattca cttattaaca agtcaaaatc ttctatgttc caagtcagaa ctttgagaga actgttatgg ggctataggg atccattttt gagtttggtt ccataccctg ttactaccac agttggtctg ttttatcctt acaacaatac tgcagatgga gtttataaag ttttcaatgg aaaagataac ataagtaaag ttgccataat cgacacatat aaaggtaaaa ggaatctgtc ctattgggaa agtcactgcg acatgattaa tggtacagat gcagcctcat ttccaccttt tgttgagaaa agccaggtat tgcagttctt ttcttctgat atttgcaggt caatctatgc tgtatttgaa tccgacgtta atctgaaagg aatccctgtg tatagatttg ttcttccatc caaggccttt gcctctccag ttgaaaaccc agacaactat tgtttctgca cagaaaaaat tatctcaaaa aattgtacat catatggtgt gctagacatc agcaaatgca aagaagggag acctgtgtac atttcacttc ctcattttct gtatgcaagt cctgatgttt cagaacctat tgatggatta aacccaaatg aagaagaaca taggacatac ttggatattg aacctataac tggattcact ttacaatttg caaaacggct gcaggtcaac ctattggtca agccatcaga aaaaattcaa gtattaaaga atctgaagag gaactatatt gtgcctattc tttggcttaa tgagactggg accattggtg atgagaaggc aaacatgttc agaagtcaag taactggaaa aataaacctc cttggcctga tagaaatgat cttactcagt gttggtgtgg tgatgtttgt tgcttttatg atttcatatt gtgcatgcag atcgaaaaca ataaaataa
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CD36 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CD36. It may not necessarily be applicable to this product.
NCBI Accession #
BC008406
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UniProt Secondary Accession #
Q13966; Q16093; Q8TCV7; Q9BPZ8; Q9BQC2; Q9BZM8; Q9BZN3; D9IX66; D9IX67; D9IX68; D9IX69[Other Products]
UniProt Related Accession #
P16671[Other Products]
Molecular Weight
46,090 Da
NCBI Official Full Name
Homo sapiens CD36 molecule (thrombospondin receptor), mRNA
NCBI Official Synonym Full Names
CD36 molecule
NCBI Official Symbol
CD36 [Similar Products]
NCBI Official Synonym Symbols
FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10
[Similar Products]
NCBI Protein Information
platelet glycoprotein 4
UniProt Protein Name
Platelet glycoprotein 4
UniProt Synonym Protein Names
Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD_antigen: CD36
Protein Family
Platelet glycoprotein
UniProt Gene Name
CD36 [Similar Products]
UniProt Synonym Gene Names
GP3B; GP4; FAT; GPIIIB; GPIV [Similar Products]
UniProt Entry Name
CD36_HUMAN
NCBI Summary for CD36
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
UniProt Comments for CD36
CD36: Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. Defects in CD36 are the cause of platelet glycoprotein IV deficiency (PG4D)[MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal. Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7). Belongs to the CD36 family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion
Chromosomal Location of Human Ortholog: 7q11.2
Cellular Component: brush border membrane; cell surface; extracellular space; Golgi apparatus; integral to plasma membrane; lipid raft; membrane; phagocytic vesicle; plasma membrane; platelet alpha granule membrane
Molecular Function: lipid binding; low-density lipoprotein binding; low-density lipoprotein receptor activity; protein binding; transforming growth factor beta binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; blood coagulation; cGMP-mediated signaling; cholesterol absorption; cholesterol transport; elevation of cytosolic calcium ion concentration; interleukin-1 beta secretion; intestinal absorption; lipoprotein transport; MyD88-dependent toll-like receptor signaling pathway; nitric oxide mediated signal transduction; platelet degranulation; positive regulation of cell-matrix adhesion; receptor internalization; receptor-mediated endocytosis; response to lipid; sensory perception of taste; sequestering of lipid; triacylglycerol transport
Disease: Coronary Heart Disease, Susceptibility To, 7; Malaria, Susceptibility To; Platelet Glycoprotein Iv Deficiency
Research Articles on CD36
1. Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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