Product Name
Activity-regulated cytoskeleton-associated protein (ARC), Recombinant Protein
Full Product Name
Recombinant Chicken Activity-regulated cytoskeleton-associated protein (ARC)
Product Gene Name
ARC recombinant protein
[Similar Products]
Product Synonym Gene Name
ARC[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-404aa, full length protein
Sequence
MQLDNVTNAG IHSFQGHRGV ANKPNVILQI GKCRAEMLEH VRRTHRHLLS EVSKQVEREL KGLQKSVGKL ENNLEDHVPT DNQRWKKSIK ACLARCQETI AHLERWVKRE MNVWKEVFFR LEKWADRLES MGGKYCPGEH GKQTVSVGVG GPEIRPSEGE IYDYALDMSQ MYALTPAPGE VPSIPQAHDS YQWVSVSEDA PASPVETQIF EDPHEFLSHL EEYLKQVGGT EEYWLSQIQN HMNGPAKKWW EYKQDSVKNW VEFKKEFLQY SEGTLTRDAI KRELDLPQKE GEPLDQFLWR KRDLYQTLYV DADEEEIIQY VVGTLQPKLK RFLSYPLPKT LEQLIQRGKE VQGNMDHSEE PSPQRTPEIQ SGDSVESMPP STTASPVPSN GTQPEPPSPP ATVI
3D Structure
ModBase 3D Structure for Q8AWC3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ARC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ARC. It may not necessarily be applicable to this product.
NCBI Accession #
NP_989763.1
[Other Products]
NCBI GenBank Nucleotide #
NM_204432.1
[Other Products]
UniProt Primary Accession #
Q8AWC3
[Other Products]
UniProt Related Accession #
Q8AWC3[Other Products]
Molecular Weight
46,307 Da
NCBI Official Full Name
activity-regulated cytoskeleton-associated protein
NCBI Official Synonym Full Names
activity regulated cytoskeleton associated protein
NCBI Official Symbol
ARC [Similar Products]
NCBI Official Synonym Symbols
ARG3.1
[Similar Products]
NCBI Protein Information
activity-regulated cytoskeleton-associated protein
UniProt Protein Name
Activity-regulated cytoskeleton-associated protein
UniProt Synonym Protein Names
ARC/ARG3.1; Activity-regulated gene 3.1 protein homolog; Arg3.1
Protein Family
AAA ATPase forming ring-shaped complexes
UniProt Gene Name
ARC [Similar Products]
UniProt Synonym Gene Names
Arg3.1 [Similar Products]
UniProt Comments for ARC
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity in an NMDA receptor-dependent manner. Required for homeostatic synaptic scaling of AMPA receptors ().
Research Articles on ARC
1. both the Arc/arg3.1 and zenk genes are induced by auditory imprinting, they are significantly up-regulated in different learning-relevant brain regions
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
