Product Name
CALCA, Polyclonal Antibody
Popular Item
Full Product Name
CALCA Antibody
Product Synonym Names
Alpha CGRP; alpha type CGRP; CALC 1; CALC A; CALC1; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related peptide I; calcitonin related polypeptide alpha; CGRP 1; CGRP; CGRP I; CGRP1; CT; katacalcin; KC
Product Gene Name
anti-CALCA antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01258
Specificity
CALCA antibody detects endogenous levels of total CALCA
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CALCA
Subcellular Location
Cytoplasmic and Secreted
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-CALCA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CALCA antibody
Function: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Similarity: Belongs to the calcitonin family.
Applications Tested/Suitable for anti-CALCA antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CALCA antibody
WB: 1:1000-3000
Western Blot (WB) of anti-CALCA antibody
Western blot analysis of CALCA using Jurkat whole lysates.
NCBI/Uniprot data below describe general gene information for CALCA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001029124.1
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NCBI GenBank Nucleotide #
NM_001033952.2
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UniProt Primary Accession #
P01258
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UniProt Secondary Accession #
Q13935; Q13937; Q52LX7; B7ZL39[Other Products]
UniProt Related Accession #
P01258; P06881[Other Products]
Molecular Weight
Observed: 15 kDa
Predicted: 16 kDa
NCBI Official Full Name
calcitonin isoform CT preproprotein
NCBI Official Synonym Full Names
calcitonin related polypeptide alpha
NCBI Official Symbol
CALCA [Similar Products]
NCBI Official Synonym Symbols
CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I
[Similar Products]
NCBI Protein Information
calcitonin; calcitonin gene-related peptide 1
UniProt Protein Name
Calcitonin
UniProt Synonym Protein Names
CalcitoninKatacalcinAlternative name(s):Calcitonin carboxyl-terminal peptide; CCP
Protein Family
Calcitonin
UniProt Gene Name
CALCA [Similar Products]
UniProt Synonym Gene Names
CALC1; CCP [Similar Products]
NCBI Summary for CALCA
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
UniProt Comments for CALCA
Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Research Articles on CALCA
1. This is the largest data set evaluating PCT in neonatal and pediatric patients on extracorporeal membrane oxygenation (ECMO). A PCT value of 0.5 ng/mL had the most utility for determining the absence or presence of a bacterial infection in the setting of ECMO with a high sensitivity and negative predictive values.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
