Full Product Name
NSDHL Antibody, HRP conjugated
Product Synonym Names
Sterol-4-alpha-carboxylate 3-dehydrogenase; decarboxylating; Protein H105e3; NSDHL; H105E3
Product Gene Name
anti-NSDHL antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q15738
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating protein (154-211AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-NSDHL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NSDHL antibody
Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.
Product Categories/Family for anti-NSDHL antibody
Cancer; Cardiovascular; Metabolism; Signal transduction
Applications Tested/Suitable for anti-NSDHL antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for NSDHL. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001123237.1
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NCBI GenBank Nucleotide #
NM_001129765.1
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UniProt Primary Accession #
Q15738
[Other Products]
UniProt Secondary Accession #
O00344; D3DWT6[Other Products]
UniProt Related Accession #
Q15738[Other Products]
Molecular Weight
41,900 Da
NCBI Official Full Name
sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
NCBI Official Synonym Full Names
NAD(P) dependent steroid dehydrogenase-like
NCBI Official Symbol
NSDHL [Similar Products]
NCBI Official Synonym Symbols
H105E3; XAP104; SDR31E1
[Similar Products]
NCBI Protein Information
sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
UniProt Protein Name
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
UniProt Synonym Protein Names
Protein H105e3
UniProt Gene Name
NSDHL [Similar Products]
UniProt Synonym Gene Names
H105E3 [Similar Products]
NCBI Summary for NSDHL
The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for NSDHL
Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.
Research Articles on NSDHL
1. Here we present the case of a 9-year-old Chinese girl born with the typical clinical features of CHILD syndrome. Evaluation of the skin lesions confirmed the diagnosis and led to identification of a heterozygous point mutation in exon 8 of the NSDHL gene.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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