Full Product Name
SCP-3 Polyclonal Antibody
Product Synonym Names
SYCP3; SCP3; Synaptonemal complex protein 3; SCP-3
Product Gene Name
anti-SCP-3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Concentration
1 mg/ml (lot specific)
Immunogen
Synthesized peptide derived from the Internal region of human SCP-3.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-SCP-3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-SCP-3 antibody
Applications Tested/Suitable for anti-SCP-3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SCP-3 antibody
WB: 1:500-1:2000, ELISA: 1:5000-1:20000
Western Blot (WB) of anti-SCP-3 antibody
Western Blot analysis of K562, 22RV1, H460 cells with SCP-3 Polyclonal Antibody.
NCBI/Uniprot data below describe general gene information for SCP-3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_035647.2
[Other Products]
NCBI GenBank Nucleotide #
NM_011517.2
[Other Products]
UniProt Secondary Accession #
Q3V2A4; Q549A7[Other Products]
UniProt Related Accession #
P70281[Other Products]
Molecular Weight
Calculated MW: 28
Observed MW: 27
NCBI Official Full Name
synaptonemal complex protein 3
NCBI Official Synonym Full Names
synaptonemal complex protein 3
NCBI Official Symbol
Sycp3 [Similar Products]
NCBI Official Synonym Symbols
Cor1; Scp3
[Similar Products]
NCBI Protein Information
synaptonemal complex protein 3
UniProt Protein Name
Synaptonemal complex protein 3
UniProt Gene Name
Sycp3 [Similar Products]
UniProt Synonym Gene Names
Scp3; SCP-3 [Similar Products]
UniProt Entry Name
SYCP3_MOUSE
UniProt Comments for SCP-3
SYCP3: Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Defects in SYCP3 are the cause of spermatogenic failure type 4 (SPGF4). An infertility disorder characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes. Belongs to the XLR/SYCP3 family.
Cellular Component: chromosome; condensed chromosome; condensed nuclear chromosome; condensed nuclear chromosome, pericentric region; lateral element; male germ cell nucleus; nucleus; synaptonemal complex; transverse filament
Molecular Function: DNA binding; protein binding; protein heterodimerization activity
Biological Process: cell cycle; cell division; chiasma formation; female meiosis chromosome segregation; female meiosis chromosome separation; female meiosis sister chromatid cohesion; lateral element assembly; meiosis; meiotic cell cycle; meiotic DNA repair synthesis; mitosis; negative regulation of apoptosis; sperm chromatin condensation; spermatogenesis; spermatogenesis, exchange of chromosomal proteins; synapsis; synaptonemal complex assembly
Research Articles on SCP-3
1. SYCP1 and SYCP3 act at the centromeres to promote the establishment and/or maintenance of centromere pairing and, by doing so, improve the segregation fidelity of mammalian meiotic chromosomes.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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