Product Name
ADAM33, Polyclonal Antibody
Full Product Name
ADAM33 Antibody
Product Synonym Names
ADAM33; C20orf153; DJ964F7.1; ADAM 33
Product Gene Name
anti-ADAM33 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9BZ11
Specificity
ADAM33 Antibody detects endogenous levels of total ADAM33
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Immunogen
A synthesized peptide derived from human ADAM33
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-ADAM33 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-ADAM33 antibody
Total protein Ab
Applications Tested/Suitable for anti-ADAM33 antibody
Western Blot (WB)
Application Notes for anti-ADAM33 antibody
Western Blot: 1:1000-3000
Western Blot (WB) of anti-ADAM33 antibody
Western blot analysis ADAM33 using HuvEc whole cell lysates
NCBI/Uniprot data below describe general gene information for ADAM33. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001269376.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001282447.2
[Other Products]
UniProt Primary Accession #
Q9BZ11
[Other Products]
UniProt Secondary Accession #
Q5JT75; Q5JT76; Q8N0W6; A0A1K6[Other Products]
UniProt Related Accession #
Q9BZ11[Other Products]
Molecular Weight
32,554 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 33 isoform gamma
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 33
NCBI Official Symbol
ADAM33 [Similar Products]
NCBI Official Synonym Symbols
C20orf153; DJ964F7.1
[Similar Products]
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 33
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 33
Protein Family
Disintegrin and metalloproteinase domain-containing protein
UniProt Gene Name
ADAM33 [Similar Products]
UniProt Synonym Gene Names
C20orf153; ADAM 33 [Similar Products]
UniProt Entry Name
ADA33_HUMAN
NCBI Summary for ADAM33
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of
biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
UniProt Comments for ADAM33
ADAM33: Genetic variations in ADAM33 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young *****s. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.24.-; Membrane protein, integral; Motility/polarity/chemotaxis; Protease
Chromosomal Location of Human Ortholog: 20p13
Research Articles on ADAM33
1. This meta-analysis demonstrates that the ADAM33 gene polymorphisms confer susceptibility to allergic rhinitis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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