AMH, Polyclonal Antibody

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

Purified by protein A column containing 0.02% NaN3.

Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.

Small volumes of anti-AMH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Sexual differentiation in human biology is determined by the Y chromosome, but hormones like anti mullerian hormone AMH further separate genders. Highly expressed in sertoli cell tissues, investigations into other tissues or regulation during embryogenesis requires a specific AMH antibody for WB or IHC detection. The AMH protein is known to be expressed in a temporal fashion and mis AMH localization may be disease initiators or accelerators. Compare our rabbit polyclonal to either goat pAb or mouse monoclonal species primary antibodies and you will understand why more scientist chose ours over mouse IgG or goat IgG multi species products. We recommend using ours directly as a conjugated antibody flow cytometry reagent and save time over anti mouse IgG or anti goat IgG steps. With our economical sizes, prices and stock availability, we have you covered. View our catalog for ordering 01 mg or 1 mg size.

Rabbit polyclonal AMH(1) antibody was raised against a 16 amino acid peptide from near the C terminal residues of human AMH protein.

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

Peptide ELISA (EIA), Western Blot (WB)

Peptide ELISA: 1:10,000-1:40,000
WB: 1:1,000-1:2,000

59,195 Da

anti-Mullerian hormone

muellerian-inhibiting factor

Muellerian-inhibiting factor

MIF; AMH; MIS  [Similar Products]

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in ***** females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]

This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.

(1) Legeai, L., Lefevre, G., Vigier, B.et, al A monoclonal antibody against human testicular anti-mullerian hormone Am J Reprod Immunol Microbiol.1988; 18(2):39-43.

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