Full Product Name
GDF7 Antibody
Product Synonym Names
Growth/differentiation factor 7; GDF-7
Product Gene Name
anti-GDF7 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q7Z4P5
Specificity
GDF7 Antibody detects endogenous levels of total GDF7 protein.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human GDF7.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-GDF7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GDF7 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GDF7 antibody
WB: 1:500~1:1000
ELISA: 1:40000
Western Blot (WB) of anti-GDF7 antibody
Western blot analysis of lysates from HT-29 cells, using GDF7 Antibody. The lane on the right is blocked with the synthesized peptide.
NCBI/Uniprot data below describe general gene information for GDF7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_878248.2
[Other Products]
NCBI GenBank Nucleotide #
NM_182828.3
[Other Products]
UniProt Primary Accession #
Q7Z4P5
[Other Products]
UniProt Related Accession #
Q7Z4P5[Other Products]
NCBI Official Full Name
growth/differentiation factor 7 preproprotein
NCBI Official Synonym Full Names
growth differentiation factor 7
NCBI Official Symbol
GDF7 [Similar Products]
NCBI Official Synonym Symbols
BMP12
[Similar Products]
NCBI Protein Information
growth/differentiation factor 7
UniProt Protein Name
Growth/differentiation factor 7
Protein Family
Growth/differentiation factor
UniProt Gene Name
GDF7 [Similar Products]
UniProt Synonym Gene Names
GDF-7 [Similar Products]
NCBI Summary for GDF7
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]
UniProt Comments for GDF7
May play an active role in the motor area of the primate neocortex.
Research Articles on GDF7
1. BMP-12 activates tenogenic pathway in human adipose stem cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
