3-oxo-5-alpha-steroid 4-dehydrogenase 1, ELISA Kit

3-oxo-5-alpha-steroid 4-dehydrogenase 1; SR type 1; Steroid 5-alpha-reductase 1; S5AR 1; SRD5A1; 1.3.1.22

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of SRD5A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9427594 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SRD5A1. The ELISA analytical biochemical technique of the MBS9427594 kit is based on SRD5A1 antibody-SRD5A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SRD5A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SRD5A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

29,459 Da

steroid 5 alpha-reductase 1

3-oxo-5-alpha-steroid 4-dehydrogenase 1

3-oxo-5-alpha-steroid 4-dehydrogenase 1

S5AR 1  [Similar Products]

Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]

SRD5A1: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. Belongs to the steroid 5-alpha reductase family.

Protein type: EC 1.3.1.22; Lipid Metabolism - androgen and estrogen; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase

Chromosomal Location of Human Ortholog: 5p15.31

Cellular Component: endoplasmic reticulum membrane

Molecular Function: 3-oxo-5-alpha-steroid 4-dehydrogenase activity; electron carrier activity

Biological Process: androgen biosynthetic process; female genitalia development; male genitalia development; progesterone metabolic process

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