Product Name
Growth Differentiation Factor 7 (GDF7), ELISA Kit
Full Product Name
Canine Growth Differentiation Factor 7 ELISA Kit
Product Gene Name
GDF7 elisa kit
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
Chromosome Location
Chromosome: 2; NC_000002.11 (20866424..20871250). Location: 2p24.1
3D Structure
ModBase 3D Structure for Q7Z4P5
Species Reactivity
Canine
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of GDF7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for GDF7 purchase
MBS019824 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Growth Differentiation Factor 7 (GDF7) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GDF7. The ELISA analytical biochemical technique of the MBS019824 kit is based on GDF7 antibody-GDF7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GDF7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GDF7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for GDF7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_878248.2
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NCBI GenBank Nucleotide #
NM_182828.2
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UniProt Primary Accession #
Q7Z4P5
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UniProt Related Accession #
Q7Z4P5[Other Products]
Molecular Weight
46,950 Da
NCBI Official Full Name
growth/differentiation factor 7 preproprotein
NCBI Official Synonym Full Names
growth differentiation factor 7
NCBI Official Symbol
GDF7 [Similar Products]
NCBI Official Synonym Symbols
BMP12
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NCBI Protein Information
growth/differentiation factor 7; GDF-7
UniProt Protein Name
Growth/differentiation factor 7
Protein Family
Growth/differentiation factor
UniProt Gene Name
GDF7 [Similar Products]
UniProt Synonym Gene Names
GDF-7 [Similar Products]
UniProt Entry Name
GDF7_HUMAN
NCBI Summary for GDF7
This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq, Jul 2008]
UniProt Comments for GDF7
GDF7: May play an active role in the motor area of the primate neocortex. Belongs to the TGF-beta family.
Protein type: Secreted, signal peptide; Cell development/differentiation; Secreted; Cytokine
Chromosomal Location of Human Ortholog: 2p24.1
Cellular Component: extracellular space
Molecular Function: protein binding; protein homodimerization activity; growth factor activity; cytokine activity; transforming growth factor beta receptor binding
Biological Process: axon guidance; cell fate commitment; positive regulation of transcription, DNA-dependent; activin receptor signaling pathway; roof plate formation; forebrain morphogenesis; BMP signaling pathway; regulation of apoptosis; branching morphogenesis of a tube; epithelial cell differentiation; regulation of MAPKKK cascade; midbrain development; spinal cord association neuron differentiation; gland morphogenesis; positive regulation of neuron differentiation; cell development; reproductive structure development; growth
Research Articles on GDF7
1. studies show that even though tenogenic (BMP 12 and BMP 13) and osteogenic (BMP2) BMPs bind the same receptors with high affinity they signal much differently and result in differential activation of osteogenic and tenogenic markers
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
