1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2 (PLCG2), ELI

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

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Small volumes of PLCG2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2610464 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2 (PLCG2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLCG2. The ELISA analytical biochemical technique of the MBS2610464 kit is based on PLCG2 antibody-PLCG2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLCG2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLCG2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

147,592 Da

phospholipase C, gamma 2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

PLC-gamma-2  [Similar Products]

PLCG2_MOUSE

PLCG2: a calcium dependent phosphatidylinositol-specific phospholipase C. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate. It is a crucial enzyme in transmembrane signaling. Phosphorylated and activated by tyrosine kinases in response to signaling through a variety of growth factor receptors and immune system receptors.

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11; Motility/polarity/chemotaxis; Phospholipase

Cellular Component: cytosol; membrane; plasma membrane

Molecular Function: phosphoinositide phospholipase C activity; phospholipase C activity; protein binding

Biological Process: activation of store-operated calcium channel activity; B cell differentiation; B cell receptor signaling pathway; elevation of cytosolic calcium ion concentration; follicular B cell differentiation; inositol trisphosphate biosynthetic process; negative regulation of programmed cell death; phosphatidylinositol biosynthetic process; positive regulation of interferon type I production; positive regulation of receptor internalization; regulation of gene expression; release of sequestered calcium ion into cytosol; response to ATP; response to lipopolysaccharide; response to magnesium ion; T cell receptor signaling pathway

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