Full Product Name
Ctns Antibody - middle region
Product Gene Name
anti-CTNS antibody
[Similar Products]
Product Synonym Gene Name
AI195360; AW049661[Similar Products]
Antibody/Peptide Pairs
Ctns peptide (MBS3232490) is used for blocking the activity of Ctns antibody (MBS3207525)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: GQVTVFLHGN HSNQTCPRIR FLVIHSRIVS IINQVIGWIY FMAWSVSFYP
3D Structure
ModBase 3D Structure for P57757
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 92%; Rabbit: 85%; Rat: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Mouse Ctns
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-CTNS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CTNS antibody
This is a rabbit polyclonal antibody against Ctns. It was validated on Western Blot
Target Description: Ctns is thought to transport cystine out of lysosomes.
Product Categories/Family for anti-CTNS antibody
Polyclonal; Membrane & Traffic;
Applications Tested/Suitable for anti-CTNS antibody
Western Blot (WB)
Western Blot (WB) of anti-CTNS antibody
Host: Rabbit
Target Name: Ctns
Sample Type: Mouse Lung lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for CTNS. It may not necessarily be applicable to this product.
NCBI Accession #
NP_112541
[Other Products]
NCBI GenBank Nucleotide #
NM_031251
[Other Products]
UniProt Primary Accession #
P57757
[Other Products]
UniProt Related Accession #
P57757[Other Products]
NCBI Official Full Name
cystinosin
NCBI Official Synonym Full Names
cystinosis, nephropathic
NCBI Official Symbol
Ctns [Similar Products]
NCBI Official Synonym Symbols
AI195360; AW049661
[Similar Products]
NCBI Protein Information
cystinosin
UniProt Protein Name
Cystinosin
Protein Family
Cystinosin
UniProt Gene Name
Ctns [Similar Products]
UniProt Entry Name
CTNS_MOUSE
UniProt Comments for CTNS
Function: Thought to transport cystine out of lysosomes.
Subcellular location: Lysosome membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the cystinosin family.Contains 2 PQ-loop domains.
Research Articles on CTNS
1. LAMP2A trafficking is regulated by cystinosin, Rab11, and RILP and that CMA up-regulation is a potential clinically relevant mechanism to increase cell survival in cystinosis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
