Product Name
14-3-3 eta (YWHAH), Blocking Peptide
Popular Item
Full Product Name
14-3-3 eta Blocking Peptide
Product Synonym Names
YWHA1; 14-3-3 protein eta; Protein AS1
Product Gene Name
YWHAH blocking peptide
[Similar Products]
14-3-3 eta peptide (MBS8236112) is used for blocking the activity of 14-3-3 eta antibody (MBS8210882)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q04917
Species Reactivity
Human, Mouse, Rat, Bovine, Monkey
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Directions for Use
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of YWHAH blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
YWHAH blocking peptide
The peptide is used to block Anti-14-3-3 eta Antibody reactivity.
Applications Tested/Suitable for YWHAH blocking peptide
Blocking (BL)
NCBI/Uniprot data below describe general gene information for YWHAH. It may not necessarily be applicable to this product.
NCBI Accession #
NP_003396.1
[Other Products]
NCBI GenBank Nucleotide #
NM_003405.3
[Other Products]
UniProt Primary Accession #
Q04917
[Other Products]
UniProt Related Accession #
Q04917[Other Products]
Molecular Weight
28,219 Da
NCBI Official Full Name
14-3-3 protein eta
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
NCBI Official Symbol
YWHAH [Similar Products]
NCBI Official Synonym Symbols
YWHA1
[Similar Products]
NCBI Protein Information
14-3-3 protein eta
UniProt Protein Name
14-3-3 protein eta
UniProt Synonym Protein Names
Protein AS1
Protein Family
14-3-3 protein
UniProt Gene Name
YWHAH [Similar Products]
UniProt Synonym Gene Names
YWHA1 [Similar Products]
UniProt Entry Name
1433F_HUMAN
NCBI Summary for YWHAH
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]
UniProt Comments for YWHAH
14-3-3 eta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes.
Protein type: Nuclear receptor co-regulator; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 22q12.3
Cellular Component: cytoplasmic vesicle membrane; cytoplasm; plasma membrane; cytosol
Molecular Function: insulin-like growth factor receptor binding; protein domain specific binding; protein binding; enzyme binding; sodium channel regulator activity; protein heterodimerization activity; actin binding; glucocorticoid receptor binding
Biological Process: intracellular protein transport; substantia nigra development; regulation of neuron differentiation; apoptosis; glucocorticoid receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of synaptic plasticity; glucocorticoid catabolic process; negative regulation of dendrite morphogenesis; regulation of sodium ion transport
Research Articles on YWHAH
1. This study identified YWHAH significantly associated loci with a
biologically plausible role in schizophrenia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
