Full Product Name
SDHC Antibody
Product Gene Name
anti-SDHC antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q99643
Other Notes
Small volumes of anti-SDHC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SDHC. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001030588.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001035511.1
[Other Products]
UniProt Primary Accession #
Q99643
[Other Products]
UniProt Secondary Accession #
O75609; Q3C259; Q3C2D8; Q3C2H4; Q5VTH3[Other Products]
UniProt Related Accession #
Q99643[Other Products]
Molecular Weight
12,474 Da
NCBI Official Full Name
succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform 2
NCBI Official Synonym Full Names
succinate dehydrogenase complex subunit C
NCBI Official Symbol
SDHC [Similar Products]
NCBI Official Synonym Symbols
CYBL; PGL3; QPS1; SDH3; CYB560
[Similar Products]
NCBI Protein Information
succinate dehydrogenase cytochrome b560 subunit, mitochondrial
UniProt Protein Name
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
UniProt Synonym Protein Names
Integral membrane protein CII-3; QPs-1; QPs1; Succinate dehydrogenase complex subunit C; Succinate-ubiquinone oxidoreductase cytochrome B large subunit; CYBL
Protein Family
Succinate dehydrogenase 2 membrane
UniProt Gene Name
SDHC [Similar Products]
UniProt Synonym Gene Names
CYB560; SDH3; QPs1; CYBL [Similar Products]
NCBI Summary for SDHC
This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2013]
UniProt Comments for SDHC
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Research Articles on SDHC
1. SDH-deficient gastrointestinal stromal tumors (GISTs) account for approximately 8% of gastric GISTs and are associated with a high rate of distant metastasis, regardless of conventional risk category.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
