Full Product Name
Gja8 antibody - N-terminal region
Product Gene Name
anti-GJA8 antibody
[Similar Products]
Product Synonym Gene Name
Aey5; Cnx50; Cx50; Lop10[Similar Products]
Antibody/Peptide Pairs
Gja8 peptide (MBS3231533) is used for blocking the activity of Gja8 antibody (MBS3206569)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: MGDWSFLGNI LEEVNEHSTV IGRVWLTVLF IFRILILGTA AEFVWGDEQS
3D Structure
ModBase 3D Structure for P28236
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Yeast, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 82%; Zebrafish: 100%
Immunogen
The immunogen is a synthetic peptide corresponding to a region of Mouse
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-GJA8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GJA8 antibody
This is a rabbit polyclonal antibody against Gja8. It was validated on Western Blot
Target Description: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Product Categories/Family for anti-GJA8 antibody
Polyclonal; Transcription Factor;
Applications Tested/Suitable for anti-GJA8 antibody
Western Blot (WB)
Western Blot (WB) of anti-GJA8 antibody
Host: Rat
Target Name: GJA8
Sample Tissue: Rat Skeletal Muscle
Antibody Dilution: 1ug/ml
Western Blot (WB) of anti-GJA8 antibody
WB Suggested Anti-Gja8 Antibody Titration: 0.2-1 ug/ml
Positive Control: Mouse Uterus
NCBI/Uniprot data below describe general gene information for GJA8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_032149
[Other Products]
NCBI GenBank Nucleotide #
NM_008123
[Other Products]
UniProt Primary Accession #
P28236
[Other Products]
UniProt Related Accession #
P28236[Other Products]
NCBI Official Full Name
gap junction alpha-8 protein
NCBI Official Synonym Full Names
gap junction protein, alpha 8
NCBI Official Symbol
Gja8 [Similar Products]
NCBI Official Synonym Symbols
Aey5; Cx50; Cnx50; Lop10
[Similar Products]
NCBI Protein Information
gap junction alpha-8 protein
UniProt Protein Name
Gap junction alpha-8 protein
UniProt Synonym Protein Names
Connexin-50; Cx50; Lens fiber protein MP70
Protein Family
Gap junction alpha-8 protein
UniProt Gene Name
Gja8 [Similar Products]
UniProt Synonym Gene Names
Cx50 [Similar Products]
UniProt Entry Name
CXA8_MOUSE
Research Articles on GJA8
1. These results suggest that expression of Cx50D47A induces ER stress, triggering activation of the PERK-ATF4 pathway, which potentially contributes to the lens pathology and leads to increased expression of anti-apoptotic factors, allowing cell survival.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
