A4GALT, Blocking Peptide

Lactosylceramide 4-alpha-galactosyltransferase; Alpha-1;4-N-acetylglucosaminyltransferase; Alpha-1;4-galactosyltransferase; Alpha4Gal-T1; CD77 synthase; Globotriaosylceramide synthase; Gb3 synthase; P1/Pk synthase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase; A4GALT; A14GALT; A4GALT1

For Research Use Only. Not for use in diagnostic procedures.

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Small volumes of A4GALT blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.

40,499 Da

alpha 1,4-galactosyltransferase

lactosylceramide 4-alpha-galactosyltransferase

Lactosylceramide 4-alpha-galactosyltransferase

A14GALT; A4GALT1; Gb3 synthase  [Similar Products]

A4GAT_HUMAN

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]

A4GALT: Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. Belongs to the glycosyltransferase 32 family.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Transferase; EC 2.4.1.228; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: membrane

Molecular Function: galactosyltransferase activity

Biological Process: plasma membrane organization and biogenesis

Disease: Blood Group, P1pk System

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