Full Product Name
COX15 Antibody
Product Gene Name
anti-COX15 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q7KZN9
Other Notes
Small volumes of anti-COX15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Western Blot (WB) of anti-COX15 antibody
Western blot analysis COX15 using HT29 whole cell lysates
NCBI/Uniprot data below describe general gene information for COX15. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001307903.1
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NCBI GenBank Nucleotide #
NM_001320974.1
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UniProt Primary Accession #
Q7KZN9
[Other Products]
UniProt Secondary Accession #
O60556; O75878; Q5TD00; Q5TD01; Q7Z3Q3; Q9NTN0; A8K6I9[Other Products]
UniProt Related Accession #
Q7KZN9[Other Products]
Molecular Weight
43,835 Da
NCBI Official Full Name
cytochrome c oxidase assembly protein COX15 homolog isoform 2
NCBI Official Synonym Full Names
COX15, cytochrome c oxidase assembly homolog
NCBI Official Symbol
COX15 [Similar Products]
NCBI Official Synonym Symbols
CEMCOX2
[Similar Products]
NCBI Protein Information
cytochrome c oxidase assembly protein COX15 homolog
UniProt Protein Name
Cytochrome c oxidase assembly protein COX15 homolog
Protein Family
Cytochrome c oxidase assembly protein
UniProt Gene Name
COX15 [Similar Products]
NCBI Summary for COX15
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region. [provided by RefSeq, Jul 2008]
UniProt Comments for COX15
May be involved in the biosynthesis of heme A.
Research Articles on COX15
1. Mutations of COX15 causing single amino acid conversions are associated with fatal infantile hypertrophic cardiomyopathy and the neurological disorder Leigh syndrome.
Precautions
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Disclaimer
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