Product Name
Keratin-pan (KRT2), Polyclonal Antibody
Full Product Name
Keratin-pan Antibody
Product Synonym Names
KRT2; KRT2A; KRT2E; Keratin; type II cytoskeletal 2 epidermal; Cytokeratin-2e; CK-2e; Epithelial keratin-2e; Keratin-2 epidermis; Keratin-2e; K2e; Type-II keratin Kb2; KRT76; KRT2B; KRT2P; Keratin; type II cytoskeletal 2 oral; Cytokeratin-2P; CK-2P; K2P; Keratin-76; K76; Type-II keratin Kb9; KRT3; Keratin; type II cytoskeletal 3; 65 kDa cytokeratin; Cytokeratin-3; CK-3; Keratin-3; K3; Type-II keratin Kb3; KRT5; Keratin; type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; K5; Type-II keratin Kb5; KRT6A; K6A; KRT6D; Keratin; type II cytoskeletal 6A; Cytokeratin-6A; CK-6A; Cytokeratin-6D; CK-6D; Keratin-6A; K6A; Type-II keratin Kb6; allergen Hom s 5; KRT6B; K6B; KRTL1; Keratin; type II cytoskeletal 6B; Cytokeratin-6B; CK-6B; Keratin-6B; K6B; Type-II keratin Kb10; KRT6C; KRT6E; Keratin; type II cytoskeletal 6C; Cytokeratin-6C; CK-6C; Cytokeratin-6E; CK-6E; Keratin K6h; Keratin-6C; K6C; Type-II keratin Kb12; KRT71; K6IRS1; KB34; KRT6IRS1; Keratin; type II cytoskeletal 71; Cytokeratin-71; CK-71; Keratin-71; K71; Type II inner root sheath-specific keratin-K6irs1; Keratin 6 irs; hK6irs; hK6irs1; Type-II keratin Kb34; KRT72; K6IRS2; KB35; KRT6; KRT6IRS2; Keratin; type II cytoskeletal 72; Cytokeratin-72; CK-72; Keratin-72; K72; Type II inner root sheath-specific keratin-K6irs2; Type-II keratin Kb35; KRT73; K6IRS3; KB36; KRT6IRS3; Keratin; type II cytoskeletal 73; Cytokeratin-73; CK-73; Keratin-73; K73; Type II inner root sheath-specific keratin-K6irs3; Type-II keratin Kb36; KRT74; K6IRS4; KB37; KRT5C; KRT6IRS4; Keratin; type II cytoskeletal 74; Cytokeratin-74; CK-74; Keratin-5c; K5C; Keratin-74; K74; Type II inner root sheath-specific keratin-K6irs4; Type-II keratin Kb37; KRT75; K6HF; KB18; Keratin; type II cytoskeletal 75; Cytokeratin-75; CK-75; Keratin-6 hair follicle; hK6hf; Keratin-75; K75; Type II keratin-K6hf; Type-II keratin Kb18; KRT79; K6L; KB38; KRT6L; Keratin; type II cytoskeletal 79; Cytokeratin-79; CK-79; Keratin-6-like; Keratin-6L; Keratin-79; K79; Type-II keratin Kb38
Product Gene Name
anti-KRT2 antibody
[Similar Products]
Product Synonym Gene Name
KRT76; KRT3; KRT5; KRT6A; KRT6B; KRT6C; KRT71; KRT72; KRT73; KRT74; KRT75; KRT79; KRT8; KRT84[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P35908
Species Reactivity
Human, Mouse, Rat
Specificity
Keratin-pan Antibody detects endogenous levels of Keratin-pan185 AND OTHERS protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human Keratin around the non-acetylation site of Lys185 AND OTHERS.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-KRT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-KRT2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-KRT2 antibody
WB: 1:500~1:1000
ELISA: 1:10000
Western Blot (WB) of anti-KRT2 antibody
Western blot analysis of lysate from Jurkat cells, using Keratin-pan Antibody.
NCBI/Uniprot data below describe general gene information for KRT2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000414.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000423.2
[Other Products]
UniProt Primary Accession #
P35908
[Other Products]
UniProt Secondary Accession #
Q4VAQ2[Other Products]
UniProt Related Accession #
P35908[Other Products]
NCBI Official Full Name
keratin, type II cytoskeletal 2 epidermal
NCBI Official Synonym Full Names
keratin 2
NCBI Official Symbol
KRT2 [Similar Products]
NCBI Official Synonym Symbols
K2e; KRTE; CK-2e; KRT2A; KRT2E
[Similar Products]
NCBI Protein Information
keratin, type II cytoskeletal 2 epidermal
UniProt Protein Name
Keratin, type II cytoskeletal 2 epidermal
UniProt Synonym Protein Names
Cytokeratin-2e; CK-2e; Epithelial keratin-2e; Keratin-2 epidermis; Keratin-2e; K2e; Type-II keratin Kb2
UniProt Gene Name
KRT2 [Similar Products]
UniProt Synonym Gene Names
KRT2A; KRT2E; CK-2e; K2e [Similar Products]
NCBI Summary for KRT2
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
UniProt Comments for KRT2
Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization.
Research Articles on KRT2
1. Report genetic/clinical spectrum of KRT2 mutations in keratinopathic ichthyosis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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