Product Name
Prostaglandin D2 receptor (Ptgdr), Recombinant Protein
Full Product Name
Recombinant Rat Prostaglandin D2 receptor (Ptgdr)
Product Gene Name
Ptgdr recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-357. Full Length
Sequence
MNESYRCQAA TWVERGSSAT MGGVAFSAGL LGNLLALVLL ARSGLGSCRP GPLHPPPSVF YVLVCGLTVT DLLGKCLISP MVLAAYAQNR SLKELLPASG NQLCEAFAFL MSFFGLASTL QLLAMALECW LSLGHPFFYQ RHITARRGVL VAPVAGAFSL AFCALPFAGF GKFVQYCPGT WCFIQMIHKK RSFSVIGFSV LYSSLMALLV LATVVCNLGA MSNLYAMHRR QRHHPRRCSR DRAQSGSDYR HGSPNPLEEL DHFVLLALTT VLFTMCSLPL IYRAYYGAFK LVDRADGDSE DLQALRFLSV ISIVDPWIFI IFRTSVFRML FHKTFTRPLI YRNWCSHSWQ TNMESTL
3D Structure
ModBase 3D Structure for Q9R261
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Ptgdr recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for Ptgdr recombinant protein
Transmembrane Protein
Application Notes for Ptgdr recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for Ptgdr. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001128636.1
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NCBI GenBank Nucleotide #
NM_001135164.1
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UniProt Primary Accession #
Q9R261
[Other Products]
UniProt Related Accession #
Q9R261[Other Products]
Molecular Weight
39,769 Da
NCBI Official Full Name
prostaglandin D2 receptor
NCBI Official Synonym Full Names
prostaglandin D2 receptor-like
NCBI Official Symbol
Ptgdr [Similar Products]
NCBI Official Synonym Symbols
RGD1565108
[Similar Products]
NCBI Protein Information
prostaglandin D2 receptor
UniProt Protein Name
Prostaglandin D2 receptor
UniProt Synonym Protein Names
Prostanoid DP receptor
Protein Family
Prostaglandin D2 receptor
UniProt Gene Name
Ptgdr [Similar Products]
UniProt Synonym Gene Names
PGD receptor; PGD2 receptor [Similar Products]
UniProt Entry Name
PD2R_RAT
UniProt Comments for Ptgdr
PTGDR: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate. Genetic variations in PTGDR are associated with susceptibility to asthma-related traits type 1 (ASRT1). Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR
Cellular Component: integral to membrane; plasma membrane
Molecular Function: prostaglandin D receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway
Research Articles on Ptgdr
1. the inhibitory effect of PGD(2) in the small intestine is mediated via activation of the DP1 receptor.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
