Product Name
NDUFAF2, Polyclonal Antibody
Full Product Name
NDUFAF2 Antibody, Biotin conjugated
Product Synonym Names
Mimitin, mitochondrial; B17.2-like; B17.2L; Myc-induced mitochondrial protein; MMTN; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; NDUFA12-like protein; NDUFAF2; NDUFA12L
Product Gene Name
anti-NDUFAF2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8N183
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Mimitin, mitochondrial protein (117-169AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-NDUFAF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NDUFAF2 antibody
Acts as a molecular chaperone for mitochondrial complex I assembly.
Product Categories/Family for anti-NDUFAF2 antibody
Cancer; Tags & Cell Markers; Metabolism; Signal transduction
Applications Tested/Suitable for anti-NDUFAF2 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for NDUFAF2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_777549.1
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NCBI GenBank Nucleotide #
NM_174889.4
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UniProt Primary Accession #
Q8N183
[Other Products]
UniProt Secondary Accession #
A8K5I1[Other Products]
UniProt Related Accession #
Q8N183[Other Products]
Molecular Weight
19,856 Da
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Synonym Full Names
NADH:ubiquinone oxidoreductase complex assembly factor 2
NCBI Official Symbol
NDUFAF2 [Similar Products]
NCBI Official Synonym Symbols
MMTN; B17.2L; mimitin; NDUFA12L
[Similar Products]
NCBI Protein Information
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
UniProt Protein Name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
UniProt Synonym Protein Names
B17.2-like; B17.2L; Mimitin
UniProt Gene Name
NDUFAF2 [Similar Products]
UniProt Synonym Gene Names
NDUFA12L; MMTN [Similar Products]
NCBI Summary for NDUFAF2
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency. [provided by RefSeq, Jul 2008]
UniProt Comments for NDUFAF2
Acts as a molecular chaperone for mitochondrial complex I assembly (PubMed:16200211). Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:16200211, PubMed:27626371).
Research Articles on NDUFAF2
1. A; p.Ala467Thr].">One patient presented with Leigh syndrome and had a homozygous deletion in the NDUFAF2 gene, while the second patient had a homozygous mutation in the POLG gene, [c.1399G>A; p.Ala467Thr].
Precautions
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Disclaimer
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