Product Name
CEACAM8, Polyclonal Antibody
Popular Item
Full Product Name
CEACAM8 Antibody
Product Synonym Names
Carcinoembryonic antigen CGM6; Carcinoembryonic antigen gene family member 6; Carcinoembryonic antigen related cell adhesion molecule 8; Carcinoembryonic antigen-related cell adhesion molecule 8; CD 66b; CD 67; CD66b; CD66b antigen; CD67; CD67 antigen; CEACAM 8; CEACAM8; CEAM8_HUMAN; CGM 6; CGM6; NCA 95; NCA95; Non-specific cross-reacting antigen NCA-95; Nonspecific cross reacting antigen NCA 95; Nonspecific cross reacting antigen NCA95
Product Gene Name
anti-CEACAM8 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P31997
Specificity
CEACAM8 antibody detects endogenous levels of total CEACAM8
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CEACAM8
Subcellular Location
Cell Membrane
Tissue Specificity
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-CEACAM8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CEACAM8 antibody
Similarity: Belongs to the immunoglobulin superfamily. CEA family.
Applications Tested/Suitable for anti-CEACAM8 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CEACAM8 antibody
WB: 1:1000-3000
IHC: 1:50-1:200
Western Blot (WB) of anti-CEACAM8 antibody
Western blot analysis of CEACAM8 using HeLa whole cell lysates

Immunohistochemistry (IHC) of anti-CEACAM8 antibody
MBS9603009 at 1/200 staining human liver tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.

NCBI/Uniprot data below describe general gene information for CEACAM8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001807.2
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NCBI GenBank Nucleotide #
NM_001816.3
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UniProt Primary Accession #
P31997
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UniProt Secondary Accession #
O60399; Q16574[Other Products]
UniProt Related Accession #
P31997[Other Products]
Molecular Weight
Observed: 38 kDa
Predicted: 39 kDa
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 8
NCBI Official Synonym Full Names
carcinoembryonic antigen related cell adhesion molecule 8
NCBI Official Symbol
CEACAM8 [Similar Products]
NCBI Official Synonym Symbols
CD67; CGM6; CD66b; NCA-95
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NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 8
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 8
UniProt Synonym Protein Names
CD67 antigen; Carcinoembryonic antigen CGM6; Non-specific cross-reacting antigen NCA-95; CD_antigen: CD66b
Protein Family
Carcinoembryonic antigen-related cell adhesion molecule
UniProt Gene Name
CEACAM8 [Similar Products]
UniProt Synonym Gene Names
CGM6 [Similar Products]
UniProt Comments for CEACAM8
Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764).
Research Articles on CEACAM8
1. Increased CD66b positive tumor-infiltrating neutrophils (CD66b + TINs) was significantly associated with presence of metastasis, S stage, and nonseminomatous germ cell tumor diagnosis.
Precautions
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Disclaimer
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