Product Name
GPR6, Polyclonal Antibody
Popular Item
Full Product Name
GPR6 Antibody
Product Synonym Names
G protein coupled receptor 6; G-protein coupled receptor 6; GPR 6; GPR6; GPR6_HUMAN; Sphingosine 1 phosphate receptor GPR 6; Sphingosine 1 phosphate receptor GPR6; Sphingosine 1-phosphate receptor GPR6
Product Gene Name
anti-GPR6 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P46095
Species Reactivity
Human, Mouse, Rat
Specificity
GPR6 antibody detects endogenous levels of total GPR6
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide
Subcellular Location
Cell Membrane. Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-GPR6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GPR6 antibody
Function: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).
Similarity: Belongs to the G-protein coupled receptor 1 family.
Applications Tested/Suitable for anti-GPR6 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GPR6 antibody
WB: 1:500-1:2000
Western Blot (WB) of anti-GPR6 antibody
Western blot analysis of GPR6 expression in A431 whole cell lysate, The lane on the left is treated with the antigen-specific peptide.
NCBI/Uniprot data below describe general gene information for GPR6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001273028.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001286099.1
[Other Products]
UniProt Primary Accession #
P46095
[Other Products]
UniProt Secondary Accession #
Q17RJ7; Q5SYL0; B4DHS9; J3KQR3[Other Products]
UniProt Related Accession #
P46095[Other Products]
Molecular Weight
Observed: 38 kDa
Predicted: 38 kDa
NCBI Official Full Name
G-protein coupled receptor 6 isoform a
NCBI Official Synonym Full Names
G protein-coupled receptor 6
NCBI Official Symbol
GPR6 [Similar Products]
NCBI Protein Information
G-protein coupled receptor 6
UniProt Protein Name
G-protein coupled receptor 6
UniProt Synonym Protein Names
Sphingosine 1-phosphate receptor GPR6
Protein Family
G-protein coupled receptor
UniProt Gene Name
GPR6 [Similar Products]
UniProt Comments for GPR6
Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons ().
Research Articles on GPR6
1. The GPR6 gene influences the reinforcement learning rate in a computational, neurogenetic model.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
