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CD4, Monoclonal Antibody

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产品名称: CD4, Monoclonal Antibody
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简单介绍

CD4, Monoclonal Antibody


CD4, Monoclonal Antibody  的详细介绍
Product Name

CD4, Monoclonal Antibody

Full Product Name

CD4 antibody (allophycocyanin)

Product Synonym Names
Rat monoclonal CD4 antibody (allophycocyanin); Monoclonal CD4 antibody; Anti-CD4 antibody; CD4; CD-4 antibody; CD 4 antibody; Ly-4 antibody; CD-4; CD4 antibody (APC); CD 4; L3T4 antibody
Product Gene Name

anti-CD4 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for Q9W6V7
Clonality
Monoclonal
Isotype
IgG2a kappa
Clone Number
RM4-5
Host
Rat
Species Reactivity
Mouse
Form/Format
Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration
500 ug/ml (lot specific)
Conjugate
APC
Preparation and Storage
Store at 2-8 degree C. Do not freeze. Protect from light.
Other Notes
Small volumes of anti-CD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-CD4 antibody
The RM4-5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of RM4-5 is blocked by GK1.5.
Product Categories/Family for anti-CD4 antibody
Immunology
Applications Tested/Suitable for anti-CD4 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-CD4 antibody
FC/FACS: = 1 ug/test
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Flow Cytometry (FC/FACS) of anti-CD4 antibody
Staining of mouse splenocytes with CD3 antibody (FITC) and 0.06 ug of Rat IgG2a K Isotype Control (left) or 0.06 ug of CD4 antibody (right). Total viable cells were used for analysis.
anti-CD4 antibody Flow Cytometry (FC/FACS) (FC/FACS) image
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NCBI/Uniprot data below describe general gene information for CD4. It may not necessarily be applicable to this product.
NCBI GI #
4539032
NCBI GeneID
395362
NCBI Accession #
CAA72740.1 [Other Products]
UniProt Primary Accession #
Q9W6V7 [Other Products]
Molecular Weight
54,985 Da
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NCBI Official Full Name
CD4
NCBI Official Synonym Full Names
CD4 molecule
NCBI Official Symbol
CD4  [Similar Products]
NCBI Protein Information
T-cell surface glycoprotein CD4
UniProt Protein Name
CD4 protein
UniProt Synonym Protein Names
CD4 protein
Protein Family
CD40 ligand
UniProt Gene Name
CD4  [Similar Products]
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Research Articles on CD4
1. Chicken CD4-positiveCD25-positive T cells have suppressive and cytokine properties similar to those of mammalian regulatory T cells.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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