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MRAS, Polyclonal Antibody

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产品名称: MRAS, Polyclonal Antibody
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简单介绍

MRAS, Polyclonal Antibody


MRAS, Polyclonal Antibody  的详细介绍
Product Name

MRAS, Polyclonal Antibody

Full Product Name

MRAS antibody

Product Synonym Names
Polyclonal MRAS; Anti-MRAS; Muscle Ras Oncogene Homolog; Mras; Flj42964; M Ras; R Ras3; Rras3
Product Gene Name

anti-MRAS antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for Q6FGP0
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
MRAS antibody was purified by Antigen Affinity chromatography
Form/Format
Supplied in PBS buffer with 0.02% Sodium Azide and 50% Glycerol, pH 7.3
Biological Significance
MRAS may serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.
Immunogen
MRAS antibody was raised in Rabbit using Human MRAS as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage and -20 degree C for long term storage. Avoid repeat freeze/thaw cycles
Other Notes
Small volumes of anti-MRAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-MRAS antibody
Rabbit polyclonal MRAS antibody
Product Categories/Family for anti-MRAS antibody
Signal Transduction; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-MRAS antibody
ELISA (EIA), Western Blot (WB)
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NCBI/Uniprot data below describe general gene information for MRAS. It may not necessarily be applicable to this product.
NCBI GI #
49457087
NCBI GeneID
22808
NCBI Accession #
CAG46864.1 [Other Products]
UniProt Primary Accession #
Q6FGP0 [Other Products]
UniProt Related Accession #
O14807[Other Products]
Molecular Weight
23,846 Da
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NCBI Official Full Name
MRAS, partial
NCBI Official Synonym Full Names
muscle RAS oncogene homolog
NCBI Official Symbol
MRAS  [Similar Products]
NCBI Official Synonym Symbols
M-RAs; RRAS3; R-RAS3
  [Similar Products]
NCBI Protein Information
ras-related protein M-Ras
UniProt Protein Name
MRAS protein
UniProt Synonym Protein Names
MRAS protein
Protein Family
Ras-related protein
UniProt Gene Name
MRAS  [Similar Products]
UniProt Entry Name
Q6FGP0_HUMAN
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NCBI Summary for MRAS
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for MRAS
MRas: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. Belongs to the small GTPase superfamily. Ras family.

Protein type: Oncoprotein; G protein, monomeric; G protein, monomeric, Ras; G protein

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: plasma membrane

Molecular Function: GTPase activity; GTP binding; GTP-dependent protein binding

Biological Process: muscle development; metabolic process; multicellular organismal development; Ras protein signal transduction; actin cytoskeleton organization and biogenesis
Research Articles on MRAS
1. The MRAS gene loci might have a minor effect in conferring susceptibility to coronary artery disease in the Chinese population.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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