Product Name
muscle RAS oncogene homolog (MRAS), Polyclonal Antibody
Full Product Name
Rabbit anti-human muscle RAS oncogene homolog polyclonal Antibody
Product Synonym Names
muscle RAS oncogene homolog; MRAS; FLJ42964; M-RAs; R-RAS3; RRAS3
Product Gene Name
anti-MRAS antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12532 / sc-8168
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-MRAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-MRAS antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for MRAS. It may not necessarily be applicable to this product.
NCBI Accession #
AAV38860.1
[Other Products]
UniProt Secondary Accession #
Q86WX8; B4DIK0[Other Products]
UniProt Related Accession #
O14807[Other Products]
Molecular Weight
15,542 Da[Similar Products]
NCBI Official Full Name
muscle RAS oncogene homolog
NCBI Official Synonym Full Names
muscle RAS oncogene homolog
NCBI Official Symbol
MRAS [Similar Products]
NCBI Official Synonym Symbols
M-RAs; RRAS3; R-RAS3
[Similar Products]
NCBI Protein Information
ras-related protein M-Ras; muscle and microspikes RAS; ras-related protein R-Ras3
UniProt Protein Name
Ras-related protein M-Ras
UniProt Synonym Protein Names
Ras-related protein R-Ras3
Protein Family
Ras-related protein
UniProt Gene Name
MRAS [Similar Products]
UniProt Synonym Gene Names
RRAS3 [Similar Products]
UniProt Entry Name
RASM_HUMAN
NCBI Summary for MRAS
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
UniProt Comments for MRAS
MRas: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. Belongs to the small GTPase superfamily. Ras family.
Protein type: Oncoprotein; G protein, monomeric; G protein, monomeric, Ras; G protein
Chromosomal Location of Human Ortholog: 3q22.3
Cellular Component: plasma membrane
Molecular Function: GTPase activity; GTP binding; GTP-dependent protein binding
Biological Process: muscle development; metabolic process; multicellular organismal development; Ras protein signal transduction; actin cytoskeleton organization and biogenesis
Research Articles on MRAS
1. Both MRAS and SHOC2 play a key role in polarized migration.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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