Full Product Name
AMN Antibody, FITC conjugated
Product Synonym Names
Protein amnionless; AMN; UNQ513/PRO1028
Product Gene Name
anti-AMN antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9BXJ7
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Protein amnionless protein (25-163AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-AMN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AMN antibody
Necessary for efficient absorption of vitamin B12 (PubMed:12590260, PubMed:14576052). Required for normal CUBN-mediated protein transport in the kidney. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity).
Product Categories/Family for anti-AMN antibody
Developmental
biology; Metabolism; Signal transduction
Applications Tested/Suitable for anti-AMN antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for AMN. It may not necessarily be applicable to this product.
NCBI Accession #
NP_112205.2
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NCBI GenBank Nucleotide #
NM_030943.3
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UniProt Primary Accession #
Q9BXJ7
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UniProt Secondary Accession #
Q6UX83[Other Products]
UniProt Related Accession #
Q9BXJ7[Other Products]
Molecular Weight
47,754 Da
NCBI Official Full Name
protein amnionless
NCBI Official Synonym Full Names
amnion associated transmembrane protein
NCBI Official Symbol
AMN [Similar Products]
NCBI Official Synonym Symbols
PRO1028; amnionless
[Similar Products]
NCBI Protein Information
protein amnionless
UniProt Protein Name
Protein amnionless
Protein Family
AMP nucleosidase
UniProt Gene Name
AMN [Similar Products]
NCBI Summary for AMN
The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008]
UniProt Comments for AMN
Necessary for efficient absorption of vitamin B12 (PubMed:12590260, PubMed:14576052). Required for normal CUBN-mediated protein transport in the kidney. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm ().
Research Articles on AMN
1. heterozygous mutations in AMN in a family from the United Kingdom with clinical features of Imerslund-Grasbeck Syndrome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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