Product Name
Heat shock factor protein 4 (HSF4), Recombinant Protein
Full Product Name
Recombinant Dog Heat shock factor protein 4 (HSF4)
Product Gene Name
HSF4 recombinant protein
[Similar Products]
Product Synonym Gene Name
HSF4[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-492aa, full length protein
Sequence
MQEAPAALPT EPGPSPVPAF LGKLWALVGD PGTDHLIRWS PSGTSFLVSD QSRFAKEVLP QYFKHSNMAS FVRQLNMYGF RKVVSIEQGG LLRPERDHVE FQHPSFVRGR EQLLERVRRK VPALRSDDGR WRPEDLGRLL GEVQALRGVQ EITEARLREL RQQNEILWRE VVTLRQSHGQ QHRVIGKLIQ CLFGPLQTGS SGAGAKRKLS LMLDEGSSCP TPAKFNTCPL PGALLQDPYF IQSPLPETTL GLSSSHRTRG PIISDIHEDS PSPDGTRLSP SSGGRREKGL ALLKEEPASP GGEGEAGLAL APNECDFCVT APPPLSVAVV QAILEGKGNF SPEGPRNAQQ PEPRGPREVP DRGTLGLDRG ARSPENLLPP MLLRAPPESV EPAGPLDVLG PSHQGREWTL MDLDMELSLM QPLGPERSET ELAVKGLNSP GPGKDSTLGA PLLLDVQAAL GGPALSLPGA LTIYSTPESR ANYLGPGANP SP
3D Structure
ModBase 3D Structure for Q1HGE8
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of HSF4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HSF4 recombinant protein
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
NCBI/Uniprot data below describe general gene information for HSF4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001041586.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001048121.1
[Other Products]
UniProt Primary Accession #
Q1HGE8
[Other Products]
UniProt Secondary Accession #
Q1HGE6; Q1HGE7[Other Products]
UniProt Related Accession #
Q1HGE8[Other Products]
Molecular Weight
45,225 Da
NCBI Official Full Name
heat shock factor protein 4
NCBI Official Symbol
HSF4 [Similar Products]
NCBI Official Synonym Symbols
NOL3
[Similar Products]
NCBI Protein Information
heat shock factor protein 4
UniProt Protein Name
Heat shock factor protein 4
UniProt Synonym Protein Names
Heat shock transcription factor 4; HSTF 4
Protein Family
Heat shock factor protein
UniProt Gene Name
HSF4 [Similar Products]
UniProt Synonym Gene Names
HSF 4; HSTF 4 [Similar Products]
UniProt Comments for HSF4
DNA-binding protein that specifically binds heat shock promoter elements (HSE).
Research Articles on HSF4
1. Deletion of HSF4 is significantly associated with cataracts and a dog carrying the mutation is approximately 17 times more likely to develop binocular cataracts than dogs that are clear of the mutation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
