Full Product Name
FBLN1 Antibody
Product Gene Name
anti-FBLN1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P23142
Other Notes
Small volumes of anti-FBLN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for FBLN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001987.2
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NCBI GenBank Nucleotide #
NM_001996.3
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UniProt Primary Accession #
P23142
[Other Products]
UniProt Secondary Accession #
P23143; P23144; P37888; Q5TIC4; Q8TBH8; Q9HBQ5; Q9UC21; Q9UGR4; Q9UH41; B0QY42; B1AHL4[Other Products]
UniProt Related Accession #
P23142[Other Products]
Molecular Weight
74,434 Da
NCBI Official Full Name
fibulin-1 isoform C
NCBI Official Synonym Full Names
fibulin 1
NCBI Official Symbol
FBLN1 [Similar Products]
NCBI Official Synonym Symbols
FBLN; FIBL1
[Similar Products]
NCBI Protein Information
fibulin-1
UniProt Protein Name
Fibulin-1
UniProt Gene Name
FBLN1 [Similar Products]
UniProt Synonym Gene Names
FIBL-1 [Similar Products]
NCBI Summary for FBLN1
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]
UniProt Comments for FBLN1
Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.
Research Articles on FBLN1
1. This study demonstrated that FBLN1 can effectively promote osteogenic differentiation of human nasal inferior turbinate-derived mesenchymal stem cells into osteoblasts.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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