Product Name
40S ribosomal protein S4 (RPS4X), Polyclonal Antibody
Full Product Name
Rabbit anti-human 40S ribosomal protein S4, X isoform polyclonal Antibody(RPS4X)
Product Synonym Names
SCR10; Single copy abundant mRNA protein; RPS4X; CCG2; RPS4; SCAR
Product Gene Name
anti-RPS4X antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P62701
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunogen
Recombinant human 40S ribosomal protein S4, X isoform protein(66-263aa)
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-RPS4X antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-RPS4X antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-RPS4X antibody
Recommended dilution: IHC:1:20-1:200
Immunohistochemistry (IHC) of anti-RPS4X antibody
Immunohistochemistry of paraffin-embedded human colon cancer using MBS1497116 at dilution 1:100
NCBI/Uniprot data below describe general gene information for RPS4X. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000998.1
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NCBI GenBank Nucleotide #
NM_001007.4
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UniProt Primary Accession #
P62701
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UniProt Secondary Accession #
P12631; P12750; P27576; P55831; Q14727; Q6IPY4[Other Products]
UniProt Related Accession #
P62701[Other Products]
Molecular Weight
29,598 Da
NCBI Official Full Name
40S ribosomal protein S4, X isoform X isoform
NCBI Official Synonym Full Names
ribosomal protein S4, X-linked
NCBI Official Symbol
RPS4X [Similar Products]
NCBI Official Synonym Symbols
S4; CCG2; RPS4; SCAR; SCR10; DXS306
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NCBI Protein Information
40S ribosomal protein S4, X isoform
UniProt Protein Name
40S ribosomal protein S4, X isoform
UniProt Synonym Protein Names
SCR10; Single copy abundant mRNA protein
Protein Family
40S ribosomal protein
UniProt Gene Name
RPS4X [Similar Products]
UniProt Synonym Gene Names
CCG2; RPS4; SCAR [Similar Products]
UniProt Entry Name
RS4X_HUMAN
NCBI Summary for RPS4X
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Comments for RPS4X
RPS4X: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Protein type: Translation; RNA-binding; Ribosomal
Chromosomal Location of Human Ortholog: Xq13.1
Cellular Component: cytosol; focal adhesion; membrane; polysome; ribonucleoprotein complex; ribosome; small ribosomal subunit
Molecular Function: rRNA binding; structural constituent of ribosome
Biological Process: cellular protein metabolic process; gene expression; mRNA catabolic process, nonsense-mediated decay; multicellular organismal development; positive regulation of cell proliferation; positive regulation of translation; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription
Research Articles on RPS4X
1. Low RPS4X expression is associated with poor disease-specific and recurrence-free survival in bladder cancer
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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