Product Name
Tumor Associated Calcium Signal Transducer 2 (TACSTD2), Recombinant Protein
Full Product Name
Recombinant Tumor Associated Calcium Signal Transducer 2 (TACSTD2)
Product Synonym Names
EGP-1; M1S1; TROP2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1; Cell surface glycoprotein Trop-2
Product Gene Name
TACSTD2 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
PSVLR AAVPKNVSVA EGKELDLTCN ITTDRADDVR PEVTWSFSRM PDSTLPGSRV LARLDRDSLV HSSPHVALSH VDARSYHLLV RDVSKENSGY YYCHVSLWAP GHNRSWHKVA EAVSSPAGVG VTWLEPDYQV YLNASKVPGF ADDPTELACR VVDTKSGEAN VRFTVSWYYR MNRRSDNVVT SELLAVMDGD WTLKYGERSK QRAQDGDFIF SKEHTDTFNF RIQRTTEEDR GNYYCVVSAW TKQRNNSWVK SKDVFS
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Predicted Molecular Mass
33.3kDa
Usage
Reconstitute in sterile PBS, pH7.2-pH7.4.
Endotoxin Level
<1.0EU per 1 ug (determined by the LAL method)
Expression System
Prokaryotic expression
Tag
two N-terminal Tags, His-tag and T7-tag
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.
Other Notes
Small volumes of TACSTD2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for TACSTD2 recombinant protein
SDS-PAGE, Western (WB), ELISA (EIA), Immunoprecipitation (IP).
SDS-Page of TACSTD2 recombinant protein
NCBI/Uniprot data below describe general gene information for TACSTD2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_064431.2
[Other Products]
NCBI GenBank Nucleotide #
NM_020047.3
[Other Products]
UniProt Secondary Accession #
O55130[Other Products]
UniProt Related Accession #
Q8BGV3[Other Products]
Molecular Weight
35,574 Da
NCBI Official Full Name
tumor-associated calcium signal transducer 2
NCBI Official Synonym Full Names
tumor-associated calcium signal transducer 2
NCBI Official Symbol
Tacstd2 [Similar Products]
NCBI Official Synonym Symbols
Ly97; EGP-1; TROP2; C80403; GA733-1
[Similar Products]
NCBI Protein Information
tumor-associated calcium signal transducer 2
UniProt Protein Name
Tumor-associated calcium signal transducer 2
UniProt Synonym Protein Names
Cell surface glycoprotein Trop-2
Protein Family
Tumor-associated calcium signal transducer
UniProt Gene Name
Tacstd2 [Similar Products]
UniProt Synonym Gene Names
Trop2 [Similar Products]
UniProt Entry Name
TACD2_MOUSE
UniProt Comments for TACSTD2
TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family.
Protein type: Receptor, misc.; Membrane protein, integral
Cellular Component: basal plasma membrane; extracellular space; integral to membrane; lateral plasma membrane; membrane; nucleus; plasma membrane
Biological Process: negative regulation of stress fiber formation
Research Articles on TACSTD2
1. studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.