Product Name
GPR98, Polyclonal Antibody
Popular Item
Full Product Name
GPR98 Antibody
Product Synonym Names
DKFZp761P0710; FEB 4; FEB4; G protein coupled receptor 98; G-protein coupled receptor 98; GPR 98; GPR98; GPR98_HUMAN; KIAA0686; MASS 1; Monogenic audiogenic seizure susceptibility 1 homolog; Monogenic audiogenic seizure susceptibility protein 1 homolog; USH 2B; USH 2C; USH2B; USH2C; Usher syndrome 2C; Usher syndrome type 2C protein; Usher syndrome type-2C protein; Very large G protein coupled receptor; Very large G protein coupled receptor 1; Very large G-protein coupled receptor 1; VLGR 1; VLGR 1b; VLGR1; VLGR1b
Product Gene Name
anti-GPR98 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8WXG9
Species Reactivity
Human, Mouse
Specificity
GPR98 antibody detects endogenous levels of total GPR98
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human GPR98
Subcellular Location
Cell Membrane
Tissue Specificity
Expressed at low levels in ***** tissues.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-GPR98 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GPR98 antibody
Function: Receptor that may have an important role in the development of the central nervous system.
Subunit Structure: Interacts with WHRN. Interacts with PDZD7.
Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Applications Tested/Suitable for anti-GPR98 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GPR98 antibody
WB: 1:1000-3000
Western Blot (WB) of anti-GPR98 antibody
Western blot analysis GPR98 using K562 whole cell lysates

NCBI/Uniprot data below describe general gene information for GPR98. It may not necessarily be applicable to this product.
NCBI Accession #
NP_115495.3
[Other Products]
NCBI GenBank Nucleotide #
NM_032119.4
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UniProt Primary Accession #
Q8WXG9
[Other Products]
UniProt Secondary Accession #
O75171; Q8TF58; Q9H0X5; Q9UL61[Other Products]
UniProt Related Accession #
Q8WXG9[Other Products]
Molecular Weight
Observed: 693 kDa
Predicted: 694 kDa
NCBI Official Full Name
G-protein coupled receptor 98
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor V1
NCBI Official Symbol
ADGRV1 [Similar Products]
NCBI Official Synonym Symbols
FEB4; GPR98; MASS1; USH2B; USH2C; VLGR1; VLGR1b
[Similar Products]
NCBI Protein Information
G-protein coupled receptor 98
UniProt Protein Name
G-protein coupled receptor 98
UniProt Synonym Protein Names
Monogenic audiogenic seizure susceptibility protein 1 homolog; Usher syndrome type-2C protein; Very large G-protein coupled receptor 1
Protein Family
G-protein coupled receptor
UniProt Gene Name
GPR98 [Similar Products]
UniProt Synonym Gene Names
KIAA0686; KIAA1943; MASS1; VLGR1 [Similar Products]
NCBI Summary for GPR98
This gene encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for GPR98
Receptor that may have an important role in the development of the central nervous system.
Research Articles on GPR98
1. Data suggest that the ADGRV1 variation contributes to epilepsy with myoclonic seizures, although the inheritance pattern may be complex in many cases. In patients with 5q14.3 deletion and epilepsy, ADGRV1 haploinsufficiency likely contributes to seizure development.
Precautions
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Disclaimer
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