vacuolar protein sorting 33 homolog B (yeast), ELISA Kit

Mouse Vacuolar protein sorting-associated protein 33B (VPS33B) ELISA kit; FLJ14848; vacuolar protein sorting 33B; vacuolar protein sorting 33B (yeast homolog) ) ; vacuolar protein sorting 33 homolog B (yeast)

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of VPS33B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9326994 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the vacuolar protein sorting 33 homolog B (yeast) (VPS33B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing VPS33B. The ELISA analytical biochemical technique of the MBS9326994 kit is based on VPS33B antibody-VPS33B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VPS33B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VPS33B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

70,526 Da

vacuolar protein sorting 33B (yeast)

vacuolar protein sorting-associated protein 33B

Vacuolar protein sorting-associated protein 33B

VP33B_MOUSE

VPS33B: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. Defects in VPS33B are the cause of arthrogryposis-renal dysfunction-cholestasis syndrome type 1 (ARCS1). ARCS1 is an autosomal recessive multisystem disorder, characterized by neurogenic arthrogryposis multiplex congenita, renal tubular dysfunction and neonatal cholestasis with bile duct hypoplasia and low gamma glutamyl transpeptidase activity. Platelet dysfunction is common. Belongs to the STXBP/unc-18/SEC1 family.

Protein type: Vesicle

Cellular Component: membrane; perinuclear region of cytoplasm; lysosome; late endosome; cytoplasm; endosome

Molecular Function: protein binding

Biological Process: vesicle-mediated transport; protein transport; lysosome localization; transport; melanosome localization; vesicle docking during exocytosis

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