Product Name
C-C chemokine receptor type 5 (CCR5), Recombinant Protein
Full Product Name
Recombinant Bovine C-C chemokine receptor type 5 (CCR5)
Product Gene Name
CCR5 recombinant protein
[Similar Products]
Product Synonym Gene Name
CMKBR5[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-352aa; full length protein
Sequence
MDYQTSTPLY DIDYGMSEPC QKLNVRQIAA RLLPPLYSLV FIFGFVGNML VVLILINCKK LKSMTDIYLL NLAISDLLFI ITIPFWAHYA ADQWVFGNTM CQLFTGFYFI GYFGGIFFII LLTIDRYLAI VHAVFALKAR TVTFGAATSV VTWVVAVFAS LPGIIFTKSQ KEGSRHTCSP HFPSSQYHFW KNFQTLKIVI LGLVLPLLVM IVCYSGIIKT LLRCRNEKKK HKAVRLIFVI MIVYFLFWAP YNIVLLLSTF QEFFGLNNCS GSNRLDQAMQ VTETLGMTHC CINPIIYAFV GEKFRNYLLR FFRKYFASRF CKGCPVFQGE APERVSSVYT RSTGEQEISV GL
3D Structure
ModBase 3D Structure for Q2HJ17
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CCR5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for CCR5 recombinant protein
Transmembrane Protein
Application Notes for CCR5 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for CCR5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001011672.2
[Other Products]
NCBI GenBank Nucleotide #
NM_001011672.2
[Other Products]
UniProt Primary Accession #
Q2HJ17
[Other Products]
UniProt Secondary Accession #
Q5MD63[Other Products]
UniProt Related Accession #
Q2HJ17[Other Products]
Molecular Weight
40,235 Da
NCBI Official Full Name
C-C chemokine receptor type 5
NCBI Official Symbol
CCR5 [Similar Products]
NCBI Protein Information
C-C chemokine receptor type 5
UniProt Protein Name
C-C chemokine receptor type 5
UniProt Synonym Protein Names
CD_antigen: CD195
Protein Family
C-C chemokine receptor
UniProt Gene Name
CCR5 [Similar Products]
UniProt Synonym Gene Names
CMKBR5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5 [Similar Products]
UniProt Entry Name
CCR5_BOVIN
UniProt Comments for CCR5
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation ().
Research Articles on CCR5
1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CCR5 expression.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
