Product Name
Alpha-L-iduronidase (Idua), Recombinant Protein
Full Product Name
Recombinant Mouse Alpha-L-iduronidase (Idua)
Product Gene Name
Idua recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
17-634. Full length of the mature protein.
Sequence
ESPYLVRVDA ARPLRPLLPF WRSTGFCPPL PHDQADQYDL SWDQQLNLAY IGAVPHSGIE QVRIHWLLDL ITARKSPGQG LMYNFTHLDA FLDLLMENQL LPGFELMGSP SGYFTDFDDK QQVFEWKDLV SLLARRYIGR YGLTHVSKWN FETWNEPDHH DFDNVSMTTQ GFLNYYDACS EGLRIASPTL KLGGPGDSFH PLPRSPMCWS LLGHCANGTN FFTGEVGVRL DYISLHKKGA GSSIAILEQE MAVVEQVQQL FPEFKDTPIY NDEADPLVGW SLPQPWRADV TYAALVVKVI AQHQNLLFAN SSSSMRYVLL SNDNAFLSYH PYPFSQRTLT ARFQVNNTHP PHVQLLRKPV LTVMGLMALL DGEQLWAEVS KAGAVLDSNH TVGVLASTHH PEGSAAAWST TVLIYTSDDT HAHPNHSIPV TLRLRGVPPG LDLVYIVLYL DNQLSSPYSA WQHMGQPVFP SAEQFRRMRM VEDPVAEAPR PFPARGRLTL HRKLPVPSLL LVHVCTRPLK PPGQVSRLRA LPLTHGQLIL VWSDERVGSK CLWTYEIQFS QKGEEYAPIN RRPSTFNLFV FSPDTAVVSG SYRVRALDYW ARPGPFSDPV TYLDVPAS
3D Structure
ModBase 3D Structure for P48441
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Idua recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Idua recombinant protein
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).
NCBI/Uniprot data below describe general gene information for Idua. It may not necessarily be applicable to this product.
NCBI Accession #
P48441.2
[Other Products]
UniProt Primary Accession #
P48441
[Other Products]
UniProt Secondary Accession #
E9QM17[Other Products]
UniProt Related Accession #
P48441[Other Products]
Molecular Weight
71,254 Da
NCBI Official Full Name
Alpha-L-iduronidase
NCBI Official Synonym Full Names
iduronidase, alpha-L-
NCBI Official Symbol
Idua [Similar Products]
NCBI Official Synonym Symbols
6030426D08
[Similar Products]
NCBI Protein Information
alpha-L-iduronidase
UniProt Protein Name
Alpha-L-iduronidase
Protein Family
Alpha-L-iduronidase
UniProt Gene Name
Idua [Similar Products]
Research Articles on Idua
1. This study demonstrated that the distribuation of bis(monoacylglycero)phosphate in brain of mucopolysaccharidosis 1 (Hurler) mouse.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
