Full Product Name
Anti-FUT2 Antibody
Product Synonym Names
SEC2; Galactoside 2-alpha-L-fucosyltransferase 2; Alpha(1,2)FT 2; Fucosyltransferase 2; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2; SE2; Secretor blood group alpha-2-fucosyltransferase; Secretor factor; Se
Product Gene Name
anti-FUT2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q10981
Specificity
Recognizes endogenous levels of FUT2 protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
Recombinant full length protein of human FUT2
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-FUT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FUT2 antibody
Rabbit polyclonal antibody to FUT2
Applications Tested/Suitable for anti-FUT2 antibody
Western Blot (WB)
Application Notes for anti-FUT2 antibody
WB: 1/500 - 1/2000
Western Blot (WB) of anti-FUT2 antibody
Western blot analysis of FUT2 expression in HT29 (A), K562 (B) whole cell lysates.
NCBI/Uniprot data below describe general gene information for FUT2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000502.4
[Other Products]
NCBI GenBank Nucleotide #
NM_000511.5
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UniProt Primary Accession #
Q10981
[Other Products]
UniProt Secondary Accession #
Q0VAG5; Q14338; Q5D0G2[Other Products]
UniProt Related Accession #
Q10981[Other Products]
Molecular Weight
37,740 Da
NCBI Official Full Name
galactoside 2-alpha-L-fucosyltransferase 2
NCBI Official Synonym Full Names
fucosyltransferase 2
NCBI Official Symbol
FUT2 [Similar Products]
NCBI Official Synonym Symbols
SE; Se2; sej; SEC2; B12QTL1
[Similar Products]
NCBI Protein Information
galactoside 2-alpha-L-fucosyltransferase 2
UniProt Protein Name
Galactoside 2-alpha-L-fucosyltransferase 2
UniProt Synonym Protein Names
Alpha(1,2)FT 2; Fucosyltransferase 2; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2; SE2; Secretor blood group alpha-2-fucosyltransferase; Secretor factor; Se
Protein Family
Fucosyltransferase
UniProt Gene Name
FUT2 [Similar Products]
UniProt Synonym Gene Names
SEC2; Se [Similar Products]
NCBI Summary for FUT2
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FUT2
Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids (PubMed:7876235). The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (PubMed:12692541, PubMed:8018146). Mediates interaction with intestinal microbiota influencing its composition (PubMed:21625510, PubMed:24733310, PubMed:22068912). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway (PubMed:7876235).
Research Articles on FUT2
1. Children with the A allele, which results in a truncated FUT2 protein, had lower risk of diarrhoea. FUT2 participates in the production of histo-blood group antigens and has previously been implicated in the susceptibility to infections, including Rotavirus and Norovirus Gene-set enrichment analysis suggested pathways
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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