Full Product Name
FUT2 Polyclonal Antibody
Product Synonym Names
SE; Se2; sej; SEC2; B12QTL1
Product Gene Name
anti-FUT2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q10981
Immunogen
Recombinant protein of human FUT2
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-FUT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FUT2 antibody
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene.
Applications Tested/Suitable for anti-FUT2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-FUT2 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
NCBI/Uniprot data below describe general gene information for FUT2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000502.4
[Other Products]
NCBI GenBank Nucleotide #
NM_000511.5
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UniProt Primary Accession #
Q10981
[Other Products]
UniProt Secondary Accession #
Q0VAG5; Q14338; Q5D0G2[Other Products]
UniProt Related Accession #
Q10981[Other Products]
NCBI Official Full Name
galactoside 2-alpha-L-fucosyltransferase 2
NCBI Official Synonym Full Names
fucosyltransferase 2
NCBI Official Symbol
FUT2 [Similar Products]
NCBI Official Synonym Symbols
SE; Se2; sej; SEC2; B12QTL1
[Similar Products]
NCBI Protein Information
galactoside 2-alpha-L-fucosyltransferase 2
UniProt Protein Name
Galactoside 2-alpha-L-fucosyltransferase 2
UniProt Synonym Protein Names
Alpha(1,2)FT 2; Fucosyltransferase 2; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2; SE2; Secretor blood group alpha-2-fucosyltransferase; Secretor factor; Se
Protein Family
Fucosyltransferase
UniProt Gene Name
FUT2 [Similar Products]
UniProt Synonym Gene Names
SEC2; Se [Similar Products]
NCBI Summary for FUT2
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FUT2
FUT2: Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values. Belongs to the glycosyltransferase 11 family. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: EC 2.4.1.69; Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: Golgi apparatus
Molecular Function: fucosyltransferase activity; galactoside 2-alpha-L-fucosyltransferase activity
Biological Process: carbohydrate metabolic process; protein amino acid glycosylation
Disease: Vitamin B12 Plasma Level Quantitative Trait Locus 1
Research Articles on FUT2
1. FUT2 genotype in patients with non-cystic fibrosis bronchiectasis was significantly associated with disease outcomes, with homozygous secretors exhibiting lower lung function, higher exacerbation number and a higher frequency of P. aeruginosa-dominated infection.
Precautions
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Disclaimer
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