Galactoside 2-Alpha-L-Fucosyltransferase 2 (FUT2), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of FUT2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9345654 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Galactoside 2-Alpha-L-Fucosyltransferase 2 (FUT2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FUT2. The ELISA analytical biochemical technique of the MBS9345654 kit is based on FUT2 antibody-FUT2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FUT2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FUT2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

37,740 Da

fucosyltransferase 2

galactoside 2-alpha-L-fucosyltransferase 2

Galactoside 2-alpha-L-fucosyltransferase 2

SEC2; Se  [Similar Products]

FUT2_HUMAN

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

FUT2: Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values. Belongs to the glycosyltransferase 11 family. 2 isoforms of the human protein are produced by alternative initiation.

Protein type: EC 2.4.1.69; Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: Golgi apparatus; integral to membrane

Molecular Function: fucosyltransferase activity; galactoside 2-alpha-L-fucosyltransferase activity

Biological Process: carbohydrate metabolic process; L-fucose catabolic process; protein amino acid glycosylation

Disease: Vitamin B12 Plasma Level Quantitative Trait Locus 1

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