C/EBP-epsilon (Ab-74), Antibody

C/EBP-e (Ab-74)

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 14; NC_000014.8 (23586515..23588820, complement). Location: 14q11.2

Rabbit

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

1 mg/ml (lot specific)

Small volumes of anti-C/EBP-epsilon antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

30,603 Da

CCAAT/enhancer binding protein (C/EBP), epsilon

CCAAT/enhancer-binding protein epsilon; c/EBP epsilon

CCAAT/enhancer-binding protein epsilon

C/EBP epsilon  [Similar Products]

CEBPE_HUMAN

The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

C/EBP-epsilon: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Belongs to the bZIP family. C/EBP subfamily.

Protein type: Transcription factor; Motility/polarity/chemotaxis; DNA-binding

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm

Molecular Function: protein homodimerization activity; protein heterodimerization activity

Biological Process: macrophage differentiation; transcription, DNA-dependent; cytokine biosynthetic process; defense response to bacterium; positive regulation of transcription from RNA polymerase II promoter; defense response; phagocytosis

Disease: Specific Granule Deficiency

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