Product Name
SSX4, cDNA Clone
Popular Item
Full Product Name
SSX4 cDNA Clone
Product Gene Name
SSX4 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgaacggag acgacgcctt tgcaaggaga cccagggatg atgctcaaat atcagagaag ttacgaaagg ccttcgatga tattgccaaa tacttctcta agaaagagtg ggaaaagatg aaatcctcgg agaaaatcgt ctatgtgtat atgaagctaa actatgaggt catgactaaa ctaggtttca aggtcaccct cccacctttc atgcgtagta aacgggctgc agacttccac gggaatgatt ttggtaacga tcgaaaccac aggaatcagg ttgaacgtcc tcagatgact ttcggcagcc tccagagaat cttcccgaag atcatgccca agaagccagc agaggaagaa aatggtttga aggaagtgcc agaggcatct ggcccacaaa atgatgggaa acagctgtgc cccccgggaa atccaagtac cttggagaag atcaacaaga catctggacc caaaaggggg aaacatgcct ggacccacag actgcgtgag agaaagcagc tggtggttta tgaagagatc agcgaccctg aggaagatga cgagtaa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SSX4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SSX4. It may not necessarily be applicable to this product.
NCBI Accession #
BC005325
[Other Products]
UniProt Secondary Accession #
Q3SYD4; Q5JQZ0; Q9UJU9; A8MYD4; B2RPE3[Other Products]
UniProt Related Accession #
O60224[Other Products]
Molecular Weight
17,918 Da
NCBI Official Full Name
Homo sapiens synovial sarcoma, X breakpoint 4, mRNA
NCBI Official Synonym Full Names
SSX family member 4
NCBI Official Symbol
SSX4 [Similar Products]
NCBI Official Synonym Symbols
CT5.4
[Similar Products]
NCBI Protein Information
protein SSX4
UniProt Protein Name
Protein SSX4
UniProt Synonym Protein Names
Cancer/testis antigen 5.4; CT5.4
UniProt Gene Name
SSX4 [Similar Products]
UniProt Synonym Gene Names
SSX4A; CT5.4 [Similar Products]
UniProt Entry Name
SSX4_HUMAN
NCBI Summary for SSX4
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for SSX4
SSX4: Could act as a modulator of transcription. Belongs to the SSX family.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xp11.23
Cellular Component: nucleus
Molecular Function: transcription corepressor activity
Research Articles on SSX4
1. SSX2, SSX3, and SSX4 are expressed only in 3.5% early-stage non-small cell lung cancer patients.
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Disclaimer
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