CCAAT-Enhancer Binding Protein Epsilon (CEBPE), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of CEBPE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9904504 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CCAAT-Enhancer Binding Protein Epsilon (CEBPE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CEBPE. The ELISA analytical biochemical technique of the MBS9904504 kit is based on CEBPE antibody-CEBPE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CEBPE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CEBPE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

30,603 Da

CCAAT/enhancer binding protein epsilon

CCAAT/enhancer-binding protein epsilon

CCAAT/enhancer-binding protein epsilon

C/EBP epsilon  [Similar Products]

The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

C/EBP-epsilon: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Belongs to the bZIP family. C/EBP subfamily.

Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity

Biological Process: cytokine biosynthetic process; defense response; defense response to bacterium; granulocyte differentiation; macrophage differentiation; phagocytosis; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter

Disease: Specific Granule Deficiency

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