Product Name
SEMA3C, Blocking Peptide
Full Product Name
SEMA3C Antibody (C-term) Blocking Peptide
Product Synonym Names
Semaphorin-3C; Semaphorin-E; Sema E; SEMA3C; SEMAE
Product Gene Name
SEMA3C blocking peptide
[Similar Products]
Product Synonym Gene Name
SEMAE[Similar Products]
Antibody/Peptide Pairs
SEMA3C peptide (MBS9225503) is used for blocking the activity of SEMA3C antibody (MBS9213479)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q99985
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Secreted.
Tissue Location
Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of SEMA3C blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SEMA3C blocking peptide
Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).
NCBI/Uniprot data below describe general gene information for SEMA3C. It may not necessarily be applicable to this product.
NCBI Accession #
Q99985.2
[Other Products]
UniProt Primary Accession #
Q99985
[Other Products]
UniProt Secondary Accession #
B4DRL8[Other Products]
UniProt Related Accession #
Q99985[Other Products]
Molecular Weight
26,255 Da
NCBI Official Full Name
Semaphorin-3C
NCBI Official Synonym Full Names
semaphorin 3C
NCBI Official Symbol
SEMA3C [Similar Products]
NCBI Official Synonym Symbols
SemE; SEMAE
[Similar Products]
NCBI Protein Information
semaphorin-3C
UniProt Protein Name
Semaphorin-3C
UniProt Synonym Protein Names
Semaphorin-E; Sema E
Protein Family
Semaphorin
UniProt Gene Name
SEMA3C [Similar Products]
UniProt Synonym Gene Names
SEMAE; Sema E [Similar Products]
UniProt Entry Name
SEM3C_HUMAN
UniProt Comments for SEMA3C
SEMA3C: a secreted protein that may be involved in cell survival mechanisms. Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain. Binds with high affinity to the receptor NRP2.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 7q21-q31
Cellular Component: extracellular space
Molecular Function: chemorepellent activity; semaphorin receptor binding
Biological Process: axon guidance; immune response; negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration; response to drug
Research Articles on SEMA3C
1. Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.
Precautions
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Disclaimer
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